Autosomal Dominant Spinocerebellar Ataxia Secondary to CACNA1G in a Patient of German Ancestry
Objective: We describe the case of a male patient of German ancestry with SCA 42. Background: Hereditary spinocerebellar ataxia (SCA) describes a heterogeneous group of…Validation of a performance-based assessment of functional ability related to cognition in Parkinson’s disease
Objective: Validate the University of California San Diego Performance-Based Skills Assessment (UPSA) in Parkinson's disease (PD) Background: Diagnostic criteria for PD dementia (PDD) require significant…Domain-specific impact of cerebral white matter hyperintensities on Parkinson’s disease cognitive functioning
Objective: In this study, we investigate the relationship between white matter hyperintensities (WMH) and Parkinson's disease (PD) cognitive impairment using a comprehensive neuropsychological battery with…Use of latent class analysis and growth mixture modeling to examine longitudinal neurocognitive trajectories in non-demented Parkinson’s disease
Objective: Examine the utility of latent class analysis (LCA) and growth mixture modeling (GMM) to elucidate cognitive phenotypes and longitudinal trajectories of cognitive change in…Association of the GBA T369M polymorphism with motor and cognitive symptoms in Parkinson’s disease
Objective: To determine whether the GBA polymorphism T369M is associated with earlier age of onset, lower cognitive performance, and more severe motor impairment in Parkinson's…18F-AV-1451 PET imaging in pre-dementia Parkinson’s disease
Objective: To describe cortical and subcortical 18F-AV-1451 binding in Parkinson’s disease patients with and without mild cognitive impairment (PD-MCI and PD-nonMCI). Background: The radioligand 18F-AV-1451…“Home made” olfactory spice discrimination test for PD
Objective: To compare the olfactory function of Parkinson’s disease (PD) patients and healthy controls by using an olfactory screening test composed of common spices. In…What impacts relationship satisfaction in Parkinsonian dementias?
Objective: To explore which aspects of well-being impact on marital relationship satisfaction among people with Parkinsonian dementias and their spouses. Background: Dyadic relationships in Parkinson’s disease…Deep brain stimulation influences on event-related potentials (P300) in Parkinson’s disease
Objective: To elucidate the electrophysiological changes for executive and inhibitory control of responses in STN-DBS patient subjected to different frequencies of electrical stimulation. Background: Deep…Effects of zonisamide, an anti-parkinsonian drug, on cognition and BPSD in DLB patients: A post-hoc analysis of DLB Ph2 study
Objective: Based on the results of a phase 2 study to evaluate the efficacy of zonisamide in improving parkinsonism accompanying dementia with Lewy Bodies (DLB),…
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