Using eye tracking to identify pupil and saccade biomarkers of neurodegenerative disease
Objective: The Ontario Neurodegeneration Research Initiative Program (1) is investigating patients with neurodegeneration (Alzheimer’s disease: AD; mild cognitive impairment: MCI; Parkinson’s disease: PD; amyotrophic lateral…Self-awareness of cognitive functions in Parkinson’s disease patients with and without mild cognitive impairment.
Objective: To examine whether Parkinson’s disease (PD) patients with or without mild cognitive impairment (MCI) show impaired self-awareness (ISA) of their cognitive abilities. Background: PD…Subjective cognitive decline reflects recent cognitive change in non-demented patients with Parkinson’s disease
Objective: We investigated whether subjective cognitive decline (SCD) can reflect recent cognitive change in patients with Parkinson’s disease (PD) who had shown non-demented cognitive performance…The Effect of Anxiety on Cognition in Parkinson’s Disease
Objective: Our study examined the effect of anxiety on cognition in Parkinson’s disease (PD) patients without cognitive impairment, mild cognitive impairment and dementia. Background: Anxiety…Interactions between amyloid-β and microglial activation in Parkinson’s disease
Objective: To evaluate the relationship between microglial activation and amyloid-β deposition in the brain using positron emission tomography (PET) in Parkinson’s disease (PD) with normal…U-shaped dopamine resting state connectivity response function related to working memory performance in adults with early-stage Parkinson’s disease
Objective: Appraise how cognitive performance and neural response is affected by nigrostriatal denervation in early-stage Parkinson’s disease (PD). Background: Cognitive dysfunction in PD is heterogeneous…General Anesthesia and Parkinson’s Disease
Objective: Postoperative cognitive dysfunction is common among the elderly. These changes may even be so severe that some elderly people actually become demented after undergoing…A PSP-like phenotype accompanies rapidly progressive dementia
Objective: We describe a patient with a progressive supranuclear palsy (PSP)-like phenotype and a rapidly progressive dementia, who was found to have an unknown CSF…Non-motor symptoms in ACDY5-associated disease
Objective: To describe non-motor symptoms in a case of ACDY5-associated disease. Background: The hereditary dyskinesia syndrome caused by an ACDY5 mutation was first described in…RBD predicts the cognitive impairment in Parkinson’s disease
Objective: To assess the relationship between the presence of Rapid eye movement sleep and behavior disorders RBD and the cognitive decline of non-demented patients with PD in…
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