Speech Markers Estimate Motor Severity and Global Cognition in Parkinson’s Disease
Objective: To utilize free speech characteristics to develop markers of motor and cognitive status in Parkinson’s disease (PD). Background: Vocal biomarkers based on speech volume,…Contact location and non-motor outcomes in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To determine whether the precise location of stimulation affects cognitive performance and mood. Background: Deep brain stimulation of the subthalamic nucleus effectively treats the…Cognitive Dysfunction is Associated with Greater Imbalance and Falls in Patients with Essential Tremor
Objective: We examined the relationship between cognitive performance and gait in essential tremor (ET). Background: ET is not exclusively a motor disorder; it is associated…Mild cognitive impairment in newly diagnosed Parkinson’s disease: a three year follow up
Objective: To evaluate the stability of mild cognitive impairment in Parkinson’s disease (PD-MCI) over time to determine its clinical utility as a marker of disease.…Quantifying reinforcement learning deficits in early stage Parkinson’s patients using a strategic decision-making task
Objective: 1.Characterize deficits in reinforcement learning processes in PD during a strategic game analogous to Rock-Paper-Scissors (RPS). 2.Examine the effects of dopaminergic (DA) treatment on…Cognitive function and impulsive-compulsive behaviors in Parkinson’s disease motor subtypes
Objective: To investigate the differences in cognitive function between tremor-dominant (TD) and akinetic-rigid (AR) subtypes of Parkinson disease (PD). Background: Higher rates of dementia, autonomic symptoms,…Cognitive impairment in early onset and familial Parkinson’s disease.
Objective: The Parkinson’s Families Project (PFP) is a large-scale cohort of early onset (symptom onset <45) and familial Parkinson’s disease (PD) patients. One aim of…Resting state functional connectivity in PD patients with and without Freezing of gait
Objective: To investigate resting state functional connectivity (rsFC) abnormalities in patients with Parkinson's disease (PD), either with (PD-FOG) or without freezing of gait (PD no-FOG). …Cognitive Mechanisms of Visual Dysfunction in Non-Demented PD Patients (PD-ND)
Objective: To conduct a comprehensive assessment of visual processing in PD-ND, including tests of low-level vision sensitive to retinal pathology, high-level object/spatial vision reflecting ventral/dorsal…Cognitive effects of GPi versus STN deep brain stimulation in Parkinson’s Disease: experience with patients with moderate cognitive impairment
Objective: To compare the cognitive effects of GPi versus STN deep brain stimulation for PD in patients with moderate cognitive impairment. Background: Patients with moderate…
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