MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Cognitive dysfunction"

  • 2016 International Congress

    Neuropsychological subgroups in non-demented Parkinson’s disease: A latent class analysis

    L. Brennan, K. Devlin, S.X. Xie, D. Mechanic-Hamilton, B. Tran, H. Hurtig, A. Chen-Plotkin, L. Chahine, J.F. Morley, J.E. Duda, D.R. Roalf, N. Dahodwala, J. Rick, J.Q. Trojanowski, P.J. Moberg, D. Weintraub (Philadelphia, PA, USA)

    Objective: Identify discrete cognitive phenotypes in a cohort of 199 non-demented Parkinson's disease (PD) patients. Background: Methods to detect early cognitive decline and account for…
  • 2016 International Congress

    Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task

    K. Janitzky, M. Lippert, A. Engelhorn, J. Tegtmeier, J. Goldschmidt, H.J. Heinze, F.W. Ohl (Magdeburg, Germany)

    Objective: In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC…
  • 2016 International Congress

    Synaptic biomarkers for cognitive decline in Lewy body dementias and Alzheimer’s disease. A mass spectrometry approach

    E. Bereczki, R.M.M. Branca, P.T. Francis, J.H. Baek, J. Lehtio, D. Aarsland (Huddinge, Sweden)

    Objective: The aim of our study is to understand the role of synaptic dysfunction in cognitive decline by comparing the whole proteome of Parkinson's disease…
  • 2016 International Congress

    Circulatory levels of BDNF correlate with cognitive deficits in people with Parkinson’s disease

    H. Khalil, M.A. Alomari, O.F. Khabour, A. Al-Hieshan, J.A. Bajwa (Irbid, Jordan)

    Objective: The aim of this study was to examine the relationship of serum BDNF levels with cognitive function. Background: Brain-derived neurotrophic factor (BDNF) is essential…
  • 2016 International Congress

    A technological solution for monitoring Parkinson’s disease: A patient-based perspective on necessity, usability and acceptability

    S. Couth, E. Poliakoff, J. Vega, C. Jay, S. Harper, R. Almutiry, T.F. Cootes, A.M. Ramsay, S.A. Kotz (Manchester, United Kingdom)

    Objective: The objectives of this study were twofold. First, to determine the feasibility of monitoring changes in how people with Parkinson's feel, think, and behave…
  • 2016 International Congress

    Mild cognitive impairment is linked with white matter degeneration in the cortico-subcortical tracts in patients with Parkinson’s disease

    A. Hanganu, J.C. Houde, V.S. Fonov, C. Degroot, B. Mejia-Constain, A.L. Lafontaine, V. Soland, S. Chouinard, L.D. Collins, M. Descoteaux, O. Monchi (Calgary, Canada)

    Objective: Evaluate the correlation between brain tractography changes in patients with Parkinson's disease (PD) with and without mild cognitive impairment (MCI). Background: Up to 40%…
  • 2016 International Congress

    Construct validity of Moca test in a sample of patients with Parkinson´s disease in Bogotá and Cali – Colombia

    B.E. Muñoz, O. Bernal, A. Castillo, J.L. Orozco (Cali, Colombia)

    Objective: To evaluate of construct validity for a sample of patients with PD in Bogotá and Cali - Colombia. Background: Parkinson´s disease (PD) is a…
  • 2016 International Congress

    Mental simulation of whole-body movements in patients with isolated cervical dystonia

    M. Esposito, C. Vitale, F. Falco, S. Corvino, R. Allocca, S. Peluso, G. Santangelo, M. Conson (Naples, Italy)

    Objective: To explore mental transformation of whole-body images in patients with isolated cervical dystonia (CD). Background: Mental transformation of bodies or of body-part images is…
  • 2016 International Congress

    Brain structural abnormalities in multiple system atrophy patients with cognitive impairment

    E. Fiorenzato, R. Biundo, L. Weis, K. Seppi, M. Onofrj, P. Cortelli, H. Kaufmann, W. Poewe, F. Krismer, G. Wenning, A. Antonini (Venice-Lido, Italy)

    Objective: To investigate the cerebral anatomical changes associated with cognitive impairment (CI) in multiple system atrophy (MSA). Background: Mild cognitive deficits are frequently reported in…
  • 2016 International Congress

    Phenotypic characteristics in GBA-associated Parkinson’s disease (PD): A study in a Greek population

    A.M. Simitsi, C. Koros, N. Papagiannakis, R. Antonelou, M. Moraitou, H. Michelakakis, M. Stamelou, L. Stefanis (Athens, Greece)

    Objective: To evaluate whether there are distinct motor and non-motor symptom characteristics in GBA-associated PD (GBA-PD) in a Greek population. Background: Mutations in the GBA1…
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