The dementia with Lewy bodies related metabolic brain pattern (DLBRP) – a multicentric validation
Objective: Dementia with Lewy bodies-related pattern (DLBRP) has been identified from the FDG PET brain imaging of DLB patients and healthy controls previously. A multicentric…How does the PPP2R2B mutation alter neuronal cytoskeletal structure in SCA12
Objective: To study the effect of the PPP2R2B mutation on human induced pluripotent stem cell (iPSC) derived neurons in SCA12 patients. Background: SCA12 is an…Association between use of Furosemide and Risk of Parkinson’s disease
Objective: Main objective of study is to check the association between furosemide use and risk of Parkinson's disease (PD) in a Finnish nationwide nested case-control…The impact of cognitive impairment and Alzheimer’s disease neuropathological changes on gait and falls in Parkinson’s disease
Objective: To investigate the association between clinical markers of cognitive impairment, severity, and distribution of Alzheimer's disease neuropathological changes (ADNC) with gait difficulties, freezing of…Clinical and Neuroimaging Biomarker Predictors of Cognitive Dysfunction In Parkinson’s Disease: A Study Using PPMI Data
Objective: This study evaluates whether clinical, biological, and neuroimaging baseline markers can predict the onset of significant cognitive-based milestones developed in these cohorts over a…Assessing the Impact of Deep Brain Stimulation on Cognitive Impairment in Parkinson’s Disease: a longitudinal study.
Objective: To longitudinally assess cognitive function post-DBS in Patients with Parkinson's Disease. Background: Parkinson's disease (PD) is a chronic neurodegenerative condition that primarily affects the…The role of cognitive functions on the outcomes of an intensive multidisciplinary rehabilitation program for people with Parkinson’s disease
Objective: This study examined relationships among cognitive functions and rehabilitation outcomes in patients with Parkinson's disease (PD) during a 4-week intensive, multidisciplinary rehabilitation program (Vicenza,…Early GBA-Related Parkinson’s Disease has a Distinct Clinical Phenotype and Cholinergic Innervation
Objective: This study aims to characterize the clinical features and cholinergic innervation of early Parkinson’s disease (PD) patients with GBA mutations (GBA-PD). Background: The GBA-PD…Nonmotor symptoms in Spinocerebellar ataxia type 12 (SCA 12)
Objective: To find the frequency and extent of depression, autonomic disturbances, and cognitive impairment in patients with SCA12 and exploring its association with motor symptoms…New α-Synuclein Strain Biomarker in Parkinson’s Disease and Related Dementia
Objective: Biomarker development for Parkinson’s disease and related dementia. Background: α-Synuclein (α-syn) strains can serve as discriminators of Parkinson's disease (PD) from other α-synucleinopathies. However,…
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