- Nocturnal Blood Pressure, Non-Dipping, Psychosis And Non-Motor Symptoms In Early Stages Of Huntington’s Disease PatientsObjective: The aim of this study was to determine the relationship between 24 h ambulatory blood pressure measurements (ABPM), i.e., absence or presence of nocturnal…
- Exploring Correlations between Mutant Huntingtin, NfL, and MRI in Huntington’s Disease: A Multimodal AnalysisObjective: This study aims to investigate correlations between mHtt and NfL levels and MRI findings in individuals at different stages of HD, including presymptomatic and…
- Longitudinal imaging of regional volumes, presynaptic terminals and glucose metabolism in brains of people with early Huntington’s diseaseObjective: To compare the sensitivity of 11C‑UCB‑J PET, 18F-FDG PET and volumetric MRI for detection of longitudinal brain changes in early Huntington’s Disease (HD). Background:…
- Levodopa-induced dyskinesia and Huntington’s chorea: link to current motor control theoriesObjective: Determine if there is a motor control hypothesis that could explain movement kinematics of Huntington’s disease (HD) chorea and Parkinson’s disease (PD) levodopa-induced dyskinesia…
- Pallidal activity as a driving force of choreic movementsObjective: To investigate the mechanisms of neuronal discharges of the globus pallidus which drive choreic movements. Background: Synchronized bursts and the low discharge rates of…
- Effects of cerebellar cTBS on motor symptoms in Huntington’s disease: a feasibility and pilot studyObjective: To evaluate the feasibility and preliminary clinical effects of a single session of cerebellar cTBS in patients with Huntington's disease (HD) with mild-moderate motor…
- Localisation of distinct brain networks in premanifest and manifest Huntington’s diseaseObjective: To map the brain networks underlying Huntington’s Disease (HD), testing whether there are distinct networks involved in premanifest and manifest disease stages. Background: HD…
- Autoimmune Chorea. Therapy with Monoclonal Antibodies: Experimental and Clinical ApproachObjective: Autoimmune chorea (AICh) resulting from the appearance of paraneoplastic antibodies in response to development of malignant tumors of various localization. Sydenham's rheumatic chorea, described…
- Diabetes Mellitus in Huntington’s disease. The Argentinean perspectiveObjective: to compare the prevalence of diabetes mellitus (DM) in a self-reported series of local Huntington disease (HD) participants in the ENROLL-HD registry with the…
- Risk and timing of manifest Huntington’s disease in patients with reduced penetrance allelesObjective: To estimate risk of Huntington’s disease (HD) over time in patients with reduced penetrance (RP) alleles (36-39 CAG repeats) overall, by individual repeat length,…
