Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…The role of the cerebellum in the pathophysiology of cortical myoclonus: a neurophysiological study.
Objective: To investigate the role of the cerebellum in the pathophysiology of cortical myoclonus (CM). Background: The putative involvement of the cerebellum in the pathogenesis…Cerebellar Structural changes in Patients with Parkinson’s disease and Essential Tremor
Objective: To assess differences in cerebellar lobar volumes in Essential tremor and Parkinson’s disease patients and investigate the relation of lobar volumes with motor symptoms.…Effect of dopamine D2-receptor antagonist and basal ganglia neuromodulation on neuronal activity in the cerebral motor area and cerebellar dentate nucleus
Objective: The effect of the D2-antagonist haloperidol on single unit activity (SU) and local field potentials (LFPs) of the cerebellar dentate nucleus and motor cortex…Relationship between symptoms and regional density of metabotropic glutamate receptors subtype 1 measured with 11C-ITMM PET in de novo Parkinson’s disease
Objective: To investigate correlations of motor and non-motor symptoms with the brain densitiesof the metabotropic glutamate receptor subtype 1 (mGluR1) in de novo Parkinson’s disease…Homozygous BZRAP1 mutations cause autosomal recessive dystonia
Objective: To report the identification of bi-allelic mutations in BZRAP1, encoding the active zone (AZ) protein RIM-binding protein 1 (RBP1), as a novel cause of…Hyperkinetic Movement Disorders in Congenital Disorders of Glycosylation
Objective: The aim of the current study was to investigate hyperkinetic movement disorders in patients affected by Congenital Disorders of Glycosylation (CDG) and to characterize…Opsoclonus and ataxia in the setting of synchronous primary malignancies
Objective: To present a rare case of opsoclonus with positive anti-Ri (ANNA-2) autoantibodies, secondary to synchronous multiple primary tumors. Background: Opsoclonus refers to involuntary, conjugate, saccadic…Cerebellar involvement in progressive supranuclear palsy and corticobasal degeneration
Objective: To investigate cerebellar involvement in vivo in patients with corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) using [18F]FDG PET. Background: Cerebellar ataxia is…Modulation of cerebellar and basal ganglia loops affects vestibular processing in Parkinson’s disease
Objective: To investigate physiology of impaired balance control in Parkinson’s Disease and its modulation by deep brain stimulation Background: Postural instability leading to falls is…
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