Evaluating the effects of deep brain stimulation (DBS) in mice with spinocerebellar ataxia (SCA1)
Objective: To determine the therapeutic effects of Deep Brain Stimulation (DBS) in mice with Spinocerebellar Ataxia (SCA1). Background: Ataxia is a movement disorder affecting balance…Deep brain stimulation in the treatment of cerebellar tremor in young patients
Objective: To investigate the efficacy of DBS on drug-resistant tremor secondary to alterations of the cerebellum or the dentato-rubro-thalamic pathways. Background: Deep Brain Stimulation (DBS)…European pediatric normative values for the scale for assessment and rating of ataxia (SARA)
Objective: To obtain international age-related normative values for the SARA in healthy European children. Background: The Scale for Assessment and Rating of Ataxia (SARA) is…Disease stage classification of the cerebellar variant of multiple system atrophy based on voxel-based morphometry
Objective: We previously reported that voxel-based morphometry (VBM) is effective for classifying the disease types causing cerebellar atrophy. In the present study, with the objective…Spinocerebellar ataxia 17: First observation in Russia
Objective: To report the detection of the first case of spinocerebellar ataxia 17 in Russian population. Background: Autosomal dominant spinocerebellar ataxias (AD SCAs) are clinically…Quantitative MRI measurement of regional cerebellar involvement in patients with progressive supranuclear palsy
Objective: We aimed to evaluate cerebellar involvement in PSP using MRI segmental volumetric analysis. Background: Progressive supranuclear palsy (PSP) is characterized clinically as postural instability…Cerebellar gray matter alterations in Huntington disease: A voxel-based morphometry study
Objective: The aim of our study is detail the cerebellar gray matter (GM) alterations in Huntington disease (HD) using the tool "spatially unbiased template atlas"…Multimodal voxel-based analysis of the infratentorial brain region in Richardson’s syndrome, progressive supranuclear palsy-parkinsonism, Parkinson variant of multiple system atrophy and Parkinson’s disease
Objective: Voxel-based analysis was applied to MRI parameters of iron content (transverse relaxation rate, R2*), microstructural integrity including mean diffusivity (MD) and fractional anisotropy (FA)…Altered cerebello-thalamo-cortical pathway in Huntington’s disease
Objective: This study aims to assess the functional integrity of the cerebello-thalamo-cortical (CTC) pathway in patients with Huntington's disease (HD) through transcranial magnetic stimulation (TMS).…Correlation among DNA methylation status and LINE-1 expression in rat brain
Objective: Our objectives were to study the transcriptional expression of L1Rn elements in different brain regions and correlate with corresponding DNA methylation levels. Methods: Real…