Association between coffee and chimarrão (yerba mate) ingestion and risk of Parkinson’s disease
Objective: To assess whether the ingestion loads (quantity x time) of coffee, and specially yerba mate in southern Brazil, reduce the risk of PD. Background:…Neuroprotective effects of coffee ingredients against rotenone-induced neurodegeneration in parkinsonian model
Objective: In this study, we examined neuroprotective effects of coffee ingredients, caffeic acid (CA) and chlorogenic acid (CGA), against rotenone-induced neurodegeneration using primary cultured cells…Yerba Mate (Ilex paraguaiensis) protects dopaminergic neurons degeneration and improve their maturation in culture
Objective: To evaluate the effect of Mate leaves extracts on the survival and maturation of dopaminergic neurons in vitro. Background: Parkinson's disease (PD) is caused…Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation
Objective: To explore the causal relationship between circadian rhythm and Parkinson's disease (PD), and coffee consumption and PD, using Mendelian randomisation (MR). Background: Circadian rhythm…Identification of putative serum biomarkers for parkin-related Parkinson’s disease by metabolome analysis
Objective: Parkin is known as the causative gene of autosomal recessive familial Parkinson’s disease (parkin-PD). It remains unclear how parkin dysfunction associates with the dopaminergic…Integration of risk factors for PD in two large longitudinal cohorts
Objective: To derive a risk score for Parkinson’s disease (PD) based on lifestyle factors and family history and assess potential multiplicative and additive interaction between…Caffeinated Drinks, LRRK2 Genotype and PD
Objective: To determine the role of caffeine containing drinks on penetrance in LRRK2-associated PD Background: LRRK2 penetrance is reduced for PD [1]. Environment and/or other…Caffeine as a Treatment for Parkinson’s Disease: A Randomized Controlled Trial (CafePD)
Objective: To assess the effects of caffeine on patients with Parkinson's disease. Background: Multiple studies have linked use of caffeine, an adenosine antagonist, to a…Headache in patients with Parkinsons disease: Pilot study results
Objective: Investigate the prevalence and characteristics of headache in PD patients, acknowledge the existing relation within the predominant laterality of the headache and side of…Personality and addictive behaviours in prodromal and early Parkinson’s disease
Objective: To determine whether the personality changes demonstrated in established Parkinson's disease (PD) are found in the earliest stages of PD and the prodromal stage.…