Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…New insight into REM-sleep atonia circuits underlying REM sleep behavior disorder in living humans
Objective: To investigate brainstem structural connectivity changes in REM sleep behavior disorder (RBD) patients using an in-vivo probabilistic brainstem nuclei atlas and 7 Tesla high…Body weight and brainstem raphe echogenicity in patients with Parkinson’s disease
Objective: We aimed to investigate and compare of body weight between normal and abnormal BR echogenicity in patients with PD. Background: Weight loss is frequent…Delayed resolution of hemifacial spasm following suboccipital craniectomy in a patient with Arnold Chiari malformation type I
Objective: We report delayed resolution of hemifacial spasm (HFS), 11 years after suboccipital decompression for Arnold-Chiari type I malformation (ACM) with brainstem compression. Background: Hemifacial…The Effects of Time-Varying Caloric Vestibular Stimulation Therapy on Cognition Impairment in Parkinson’s Disease
Objective: To evaluate the potential efficacy of a software-controlled, solid-state, time-varying caloric vestibular stimulation (tvCVS) device for the treatment of cognitive impairment in Parkinson’s disease…Structural connectome of brainstem nuclei in REM sleep behavior disorder, a model of premanifest synucleinopathy
Objective: To investigate in vivobrainstem structural connectivity changes in a model of premanifest synucleinopathy, REM sleep behavior disorder (RBD), using 7 T high spatial-resolution diffusion-tensor-imaging (DTI)…Focus on the Locus: Ultra-high field MRI evaluation of locus coeruleus structure and function in Parkinson’s Disease
Objective: To develop an imaging protocol for 7 tesla magnetic resonance imaging (MRI) that captures the structural and functional consequences of locus coeruleus (LC) neurodegeneration.…Neuromelanin-MRI in REM sleep behaviour disorder predicts dopaminergic dysfunction and clinical risk of Parkinson’s disease
Objective: To determine whether neuromelanin-MRI signal changes in the substantia nigra and locus coeruleus in patients with REM sleep behaviour disorder (RBD) are predictive of…Severe Gliosis following PPN-DBS
Objective: Neuropathological investigation of tissue changes in a case with pedunculopontine nucleus (PPN) DBS placed to address axial Parkinson’s disease symptoms and freezing of gait.…Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the raphe nuclei
Objective: To investigate whether apathy is related to serotonin depletion in the raphe nuclei in patients with rapid eye movement sleep behaviour disorder (RBD), a…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.