Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…New insight into REM-sleep atonia circuits underlying REM sleep behavior disorder in living humans
Objective: To investigate brainstem structural connectivity changes in REM sleep behavior disorder (RBD) patients using an in-vivo probabilistic brainstem nuclei atlas and 7 Tesla high…Body weight and brainstem raphe echogenicity in patients with Parkinson’s disease
Objective: We aimed to investigate and compare of body weight between normal and abnormal BR echogenicity in patients with PD. Background: Weight loss is frequent…Delayed resolution of hemifacial spasm following suboccipital craniectomy in a patient with Arnold Chiari malformation type I
Objective: We report delayed resolution of hemifacial spasm (HFS), 11 years after suboccipital decompression for Arnold-Chiari type I malformation (ACM) with brainstem compression. Background: Hemifacial…Structural connectome of brainstem nuclei in REM sleep behavior disorder, a model of premanifest synucleinopathy
Objective: To investigate in vivobrainstem structural connectivity changes in a model of premanifest synucleinopathy, REM sleep behavior disorder (RBD), using 7 T high spatial-resolution diffusion-tensor-imaging (DTI)…Focus on the Locus: Ultra-high field MRI evaluation of locus coeruleus structure and function in Parkinson’s Disease
Objective: To develop an imaging protocol for 7 tesla magnetic resonance imaging (MRI) that captures the structural and functional consequences of locus coeruleus (LC) neurodegeneration.…The Effects of Time-Varying Caloric Vestibular Stimulation Therapy on Cognition Impairment in Parkinson’s Disease
Objective: To evaluate the potential efficacy of a software-controlled, solid-state, time-varying caloric vestibular stimulation (tvCVS) device for the treatment of cognitive impairment in Parkinson’s disease…Feasibility and Efficacy of Brainstem Modulation Therapy for the Management of Parkinson’s Disease
Objective: To evaluate the feasibility and potential efficacy of a software-controlled, solid-state caloric vestibular stimulation (CVS)-mediated brainstem modulation device for the treatment of non-motor and…Neuromelanin-MRI in REM sleep behaviour disorder predicts dopaminergic dysfunction and clinical risk of Parkinson’s disease
Objective: To determine whether neuromelanin-MRI signal changes in the substantia nigra and locus coeruleus in patients with REM sleep behaviour disorder (RBD) are predictive of…Severe Gliosis following PPN-DBS
Objective: Neuropathological investigation of tissue changes in a case with pedunculopontine nucleus (PPN) DBS placed to address axial Parkinson’s disease symptoms and freezing of gait.…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.