Association between actively and passively monitored hand gestures in early Parkinson’s disease
Objective: To determine the reliability and preliminary validity of passively acquired smartwatch-based sensor features of hand gestures in early Parkinson’s disease (PD). Background: Hand movements…Wearable sensor monitoring in denovo Parkinson’s disease using the Parkinson’s KinetiGraph: pilot data and correlations from the MoNS-PD cohort
Objective: To describe Parkinson’s kinetograph utilised clinical parameters and correlations in a denovo Parkison’s disease (PD) cohort from Moscow Russia. Background: The Parkinson’s KinetiGraph™ (PKG)…Kinematic assessment of bradykinesia in essential tremor compared to Parkinson’s disease: a cluster analysis
Objective: We aimed to evaluate the bradykinesia features in ET by clinical examination and kinematic analysis of repetitive finger movements. We compared data collected in…Motor onset of Parkinsonʼs disease: Is there a somatotopic pattern?
Objective: To study the clinical onset and progression of motor manifestations in different body regions in early PD patients. Background: The vulnerability of the nigrostriatal…Quantifying movement to measure Parkinson’s Disease severity and progression in a Phase 2 Study (SPARK)
Objective: To develop and evaluate objective measures of Parkinson’s disease (PD) severity and progression by applying dynamical systems analysis to inertial sensor kinematic data. Background:…Application of PKG System for Objective Measurement and Early Identification in Parkinson’s Disease
Objective: This study aimed to assess the correlations of the PKG data with clinical scores of bradykinesia, rigidity and tremor. Background: The treatment of levodopa…Passive monitored daily motor behavior significantly relates to quality of life in early Parkinson’s disease
Objective: To investigate whether passively acquired measures of gait and hand gestures are associated with health-related quality of life (HrQoL; PDQ-39) and health-state (EQ-5D-5L) in…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…Ceftriaxone improves motor function in a rat hemi-parkinsonian model: Potential to delay bilateral progression of motor deficits in Parkinson’s disease
Objective: This study sought to evaluate the impact of ceftriaxone, as a potential repurposed drug, in ameliorating motor decline in a unilateral rat 6-hydroxydopamine (6-OHDA)…Emerging motor dysfunction in those at-risk of Parkinson’s disease: 5-year follow-up of PREDICT-PD participants
Objective: To determine how motor features emerge over time in individuals estimated to be at higher risk of Parkinson’s disease (PD), compared with lower risk…
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