Wearable Devices in Movement Disorder Trials to Provide Objective Measures
Objective: To understand the validity of wearable devices in capturing objective motor and nonmotor symptoms of Parkinson’s Disease (PD) in addition to what has been…Compartment-specific blockade of dopamine uptake in nigrostriatal pathway reveals role for nigral dopamine function in movement frequency in open-field
Objective: Inhibition of tyrosine hydroxylase activity in the substantia nigra (SN) produces a significant reduction in locomotor motor activity commensurate with decreased dopamine (DA) content…Smartphone-based context awareness to improve ambulatory Parkinson’s monitoring
Objective: To determine the utility of context-awareness algorithms based on sensors in smartphones to improve ambulatory Parkinson’s disease (PD) monitoring. Background: Previous research shows that optimal motion sensor-based ambulatory PD monitoring requires multiple sensors to…Rate of Neuromuscular Excitation during Cycling Related to Mobility in Parkinson’s Disease
Objective: Aim 1 was to compare rates of neuromuscular excitation during cycling at maximum pedaling speeds between people with Parkinson’s disease (PD) who are fast…Passively measuring motor behavior in daily life: preliminary reliability and validity in individuals recently diagnosed with Parkinson’s disease
Objective: The purpose of this study was to determine the reliability and clinical validity of smartphone- and smartwatch-based, passively acquired measures of motor behavior in…Driving motor rhythms modulates bradykinesia and cortical excitability in Parkinson’s disease
Objective: To test whether driving beta (β) and gamma (γ) rhythms of the primary motor cortex (M1) by using transcranial alternating current stimulation (tACS) modulates…Slow Motion Analysis of Repetitive Tapping (SMART) test: a new means to assess bradykinesia
Objective: To develop a quantitative and objective tool to track repetitive tapping movement (RTM) using a slow motion capture and compare patients with Parkinson’s disease…Rhythmic movements decompose in Parkinson’s disease with worse disease severity at low frequencies: akinesia or impaired ability to move more slowly than comfortable?
Objective: To explore the relationship between disease severity, minimum comfortable velocity and dwell time in Parkinson's disease. Background: People find it hard to move smoothly…Association between actively and passively monitored gait in early Parkinson’s disease
Objective: To determine the the reliability and preliminary validity of passively acquired sensor features of gait in individuals with early Parkinson’s disease (PD). Background: Passive…The Many Faces of Bradykinesia in Parkinson’s Disease : The Quantitative Analysis from A Keyboard Typing Test
Objective: To explore the characteristics of bradykinesia in PD via a keyboard typing test. Background: Bradykinesia is one of the cardinal symptoms in Parkinson’s disease…
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