Frequency dependent interindividual variability of the deep brain stimulation effect on upper-limb bradykinesia
Objective: To demonstrate that there are interindividual differences in the response of upper limb bradykinesia to subthalamic deep brain stimulation (STN-DBS) in patients with Parkinson’s…High-beta Oscillations Predict Outcome of Subthalamic Deep Brain Stimulation in Parkinson’s Disease
Objective: We evaluated whether low-β and high-β band activity recorded from the subthalamic nucleus (STN) region predicts efficacy of deep brain stimulation (DBS) in Parkinson's…Overnight stimulation: a new rescue strategy for deep brain stimulation-induced bradykinesia in dystonia?
Objective: We report the serendipity case of overnight stimulation for the management of stimulation-induced bradykinesia in two patients with generalized dystonia and clinically-effective pallidal deep…Validation of the PD Home Diary for Assessment of Motor Fluctuations in Advanced Parkinson’s Disease
Objective: To determine the validity of the Parkinson’s disease (PD) home diary for quantification of motor states in patients with advanced PD and motor fluctuations.…TREMOR AND BRADYKINESIA ARE TWO UNRELATED SIDE EFFECTS INDUCED BY VALPROATE INTAKE
Objective: To better characterize clinical and neurophysiological features of valproate-induced tremor in patients with epilepsy and the effect of valproate on the execution of voluntary…Anatomical Substrates for Motor Subcomponents of Bradykinesia in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Simulation
Objective: To evaluate distinct anatomical substrates modulating motor subcomponents of bradykinesia following Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD). Background: PD…Exploratory analysis of the effect of delayed-start prasinezumab on motor sign progression measured with the Roche PD Mobile Application v2: PASADENA Phase II Parts 1 and 2
Objective: To determine whether the positive effects of prasinezumab on motor progression measured by Roche PD Mobile Application (PASADENA study Part 1; 0-52 weeks; NCT03100149)…EFFECTS OF OPICAPONE IN PARKINSON DISEASE AS ASSESSED BY KINEMATIC TECHNIQUES
Objective: We aimed to objectively investigate the effects of Opicapone on bradykinesia in Parkinson's Disease (PD) by kinematic analysis. Background: By increasing L-dopa bioavailability, catechol-O-methyl…Remote keyboard tapping: potential signatures of early motor dysfunction in isolated REM sleep behaviour disorder
Objective: To compare keyboard tapping performance in people with iRBD with controls. Background: The Distal Finger Tapping (DFT)1 test and BRadykineisa Akinesia Incoordination test (BRAIN)2…Ocular ping pong movement to disentangle apathy from Bradykinesia in Parkinson’s disease
Objective: To disentangle bradykinesia from apathy through analysis of ocular movements. Background: While Parkinson's disease (PD) is mainly characterized by motor symptoms such as bradykinesia,…
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