Successful passive monitoring of early-stage Parkinson’s disease patient mobility in Phase I RG7935/PRX002 clinical trial with smartphone sensors
Objective: Smartphone-based assessments and sensors have the potential to enable remote, passive monitoring of gait and mobility in early-stage Parkinson’s disease (PD) patients. Such sensor…Acquisition, Validation and Preprocessing of Wrist-Worn Sensor Data in Patients with Parkinson’s Disease and Healthy Controls
Objective: We describe relevant aspects and data processing steps for accelerometry and gyroscopy recordings made with a wrist-worn low-cost sensor device. In order to generalize…Impaired intracortical inhibition is associated with reduced hand dexterity in Parkinson’s disease patients
Objective: To check whether hand dexterity in Parkinson’s disease (PD) patients is linked with motor cortex excitability and plasticity. Background: Hand dexterity is impaired in…Post-movement beta rebound inhibits future movement
Objective: To evaluate the potential inhibitory effect of post-movement beta rebound (PMBR) on future movement production. Background: Changes in the cortical power of beta oscillations within the…Reliability of Continuous Parkinson’s Assessment Using Wearables
Objective: To evaluate test-retest reliability and determine the optimal number of days of use for wearable sensors and a mobile software app to continuously and…The brain plasticity for controlling reach-to-grasp functions of Parkinson’s disease
Objective: To investigate the brain plasticity for controlling the dominant and non-dominant hand muscles and reach-to-grasp (RTG) functions in Parkinson’s disease (PD). Background: Previous studies…Assessing Parkinson’s disease motor symptoms using supervised learning algorithms
Objective: Implantable brain stimulators are now an established method of treating Parkinson’s Disease (PD). Determination of optimal neural stimulation parameters is complex and clinically demanding. The goal of…Wearable motion quantification and electronic diaries for long-term monitoring of Parkinson’s disease
Objective: To clinically assess wearable motion sensors for measuring tremor, dyskinesia, slowness, and mobility and an electronic diary for Parkinson’s disease (PD) Background: A patient…Wearable sensor-based therapy titration for Parkinson’s Disease
Objective: To describe a home-based method for improved Parkinson’s therapy titration. Background: Many patients with Parkinson’s disease, due to the location of their residence or…Objective Measurement in Clinical Care of Patients with Parkinson’s disease: an RCT using the PKG
Objective: To use the Parkinson’s KinetiGraph™ (Global Kinetics CorporationTM, Australia) to help identify uncontrolled Parkinson’s disease (PD) symptoms and assist changes in clinical management leading…
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