Neural correlates of movement sequence kinematics in substantia nigra dopaminergic cells
Objective: To develop a new behavioral task for assessment of mice forelimb movements, and evaluate the substantia nigra pars compacta dopaminergic cells’ (SNpc) correlates of…Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease
Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…Death in patients with Parkinson’s disease – an observational study
Objective: We aimed to analyse the major cause and contributory reasons for death in patients with Parkinson’s disease (PD) who were known to our PD…Noladin ether attenuates MPTP -induced motor deficit by abrogating pro-inflammatory cytokines and striatal neurochemical alterations in rats
Objective: The present study was designed to investigate the therapeutic potential of noladin ether- a putative endocannabinoid against MPTP-induced behavioral, biochemical and neurochemical alterations in…Ambulatory movement measurement in evaluating deep brain stimulation effect in patients with advanced Parkinson’s disease
Objective: To assess the use of the Parkinson's Kinetigraph™ (PKG™) in evaluating the effect of deep brain stimulation (DBS) in patients with advanced Parkinson's disease (PD). Background: Assessment of the effect of DBS on bradykinesia…Non-motor symptoms in the first neurology consultation in Cali – Colombia
Objective: To describe the distribution of NMS of PD in patients assisted by the Outpatient Neurology Service between 2012 and 2016 in a high level hospital…Deep Learning in Objective Classification of Spontaneous Movement of Patients with Parkinson’s Disease Using Large-Scale Free-Living Sensor Data
Objective: Our goal was to classify spontaneous movement using a commercially available motion sensor in a clinically meaningful 3-/9-step discrete scale (SMS-3/SMS-9). Background: Brady-hypokinetic and dyskinetic…Successful passive monitoring of early-stage Parkinson’s disease patient mobility in Phase I RG7935/PRX002 clinical trial with smartphone sensors
Objective: Smartphone-based assessments and sensors have the potential to enable remote, passive monitoring of gait and mobility in early-stage Parkinson’s disease (PD) patients. Such sensor…Acquisition, Validation and Preprocessing of Wrist-Worn Sensor Data in Patients with Parkinson’s Disease and Healthy Controls
Objective: We describe relevant aspects and data processing steps for accelerometry and gyroscopy recordings made with a wrist-worn low-cost sensor device. In order to generalize…Impaired intracortical inhibition is associated with reduced hand dexterity in Parkinson’s disease patients
Objective: To check whether hand dexterity in Parkinson’s disease (PD) patients is linked with motor cortex excitability and plasticity. Background: Hand dexterity is impaired in…
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