Acute concomitant presentation of chorea and subacute combined degeneration secondary to vitamin B12 deficiency
Objective: To describe an exceptional presentation of vitamin B12 deficiency. Background: Vitamin B12 deficiency typically presents with subacute combined degeneration (SCD). Extrapyramidal symptoms are rare,…Neuroprotective role of cinnamaldehyde against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease
Objective: The present study examined the potential therapeutic effects of CA against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD and explored…REM sleep-related episodes in children with Narcolepsy type 1 after treatment with Sodium Oxybate
Objective: We aimed to analyze the effect of Sodium Oxybate (SO) on motor events occurring during nighttime in children affected with Narcolepsy type 1 (NT1).…Rotenone model of Parkinson’s disease: The dosing options in mice revisited
Objective: In the present study we have used various dosing protocols to induce the PD-like symptoms with the administration of rotenone in mice. Background: Parkinson's…Comparative study of the cognitive and behavioral disturbances between progressive supranuclear palsy phenotypes
Objective: Explore cognitive and behavioural disturbances between subtypes of progressive supranuclear palsy (PSP). Background: Although clinical diagnosis of PSP is based on specific motor symptoms,…Telepsychiatry for Patients with Parkinson’s disease
Objective: To demonstrate the feasibility of telemedicine for treatment of psychiatric co-morbidities in Parkinson’s disease and evaluate patient satisfaction with telepsychiatry. Background: Parkinson’s disease (PD)…Impulsive-compulsive behaviors in patients with Parkinson´s disease in Kannur, India
Objective: The main aim of the project was to determine the frequency of impulsive compulsive behaviors (ICB) in patients with Parkinson´s disease (PD) in Kannur,…D2 receptor mediated DARPP32/PP1α signaling is responsible for cadmium induced Parkinson’s like behavioral alterations in rats
Objective: To identify the specificity of dopamine D2 receptor mediated signaling in cadmium mediated motor alterations Background: Cadmium, a heavy metal, is to known to…Predictors for psychosis in Huntington’s disease: preliminary analysis of the Enroll-HD database.
Objective: To evaluate predictors for psychosis in HD. Background: Behavioral problems are present across all stages of HD, even preceding the development of the motor…Development of nano-formulation containing crocetin for the protective and beneficial effect against 6-hydroxydopamine induced Parkinson’s disease model via altered the genetic backgrounds
Objective: Parkinson’s disease (PD) induced by the interaction between the number of factors viz., aging, genetics toxins, mitochondrial deformity and oxidative stress. Various evidences suggest…
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