The Neuroprotective Effects of Rolipram, a Selective Phosphodiesterase IV Inhibitor, on Parkinson’s Disease in Rat Models: A Pharmacological Exploration in both In vivo and In vitro Settings
Objective: Our research sought to unravel the pharmacological effects and mechanisms of action of Rolipram through both in vivo and in vitro experimentation in models…Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model
Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…Gender Disparities in Quality of Life Domains Among Hispanic Individuals with Parkinson’s Disease: A Comparative Analysis
Objective: This study aims to determine gender differences in the quality of life of Parkinson's disease (PD) among Hispanic individuals. Background: PD profoundly affects various…Visual Temporal Discrimination Threshold using a Virtual Reality Paradigm in Cervical Dystonia
Objective: To develop a Virtual Reality (VR) application to test temporal discrimination thresholds in cervical dystonia patients within an outpatient environment. Background: Temporal discrimination threshold…Dysfluent Writing Behavior Associates with Reduced Striatal-cerebellar Connectivity in Writer’s Cramp Dystonia
Objective: The primary objective of this study was to identify the brain regions contributing to dysfluent writing behavior in a subtype of dystonia called writer’s…Study of Relationship Between Homocysteine, Folic Acid And Vitamin B12 Levels In Serum of Juvenile HD Children.
Objective: Our objective is to estimate the level of Hcy ,vitamin B12 , folic acid with motor and non-motor symptoms in HD patients in school…Clinical and Epidemiological Aspects of Neuropsychiatric Features in Patients with Huntington Disease in Chile
Objective: To describe the prevalence of motor and neuropsychiatric symptoms in HD patients seen at the Center of Movement Disorders (CETRAM), Santiago, Chile. Background: There…Clinico- radiological profile of four patients with CSF1R- related leukoencephalopathy: A case series from India
Objective: We aimed to describe the clinical, radiological and genetic profile of patients with CSF1R- related leukoencephalopathy. Background: CSF1R- related leukoencephalopathy is a rare dominantly…Evaluating the efficacy of dextromethorphan/quinidine (DM/Q) in treating irritability in Huntington’s disease
Objective: To prove the efficacy and safety of dextromethorphan/quinidine 20mg/10mg (Nuedexta®) in patients with irritability due to HD. Background: Irritability is one of HD's most…Needs and priorities of people with Parkinson’s and care partners regarding neuropsychiatric symptoms
Objective: To examine the experiences of people with Parkinson’s disease (PD) and care partners (CPs) regarding cognitive, mood, behavioral, and sleep issues. Background: Neuropsychiatric symptoms…
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