Associations of Genetic, Epigenetic and Phenotypic Measures in the Dominican Republic PKAN Cohort
Objective: To explore relationships between demographic, clinical and behavioral phenotypes and underlying genetic and epigenetic features, utilizing a large cohort of PKAN patients. Background: PKAN…Acute unilateral involuntary movement in a patient with posterior reversible encephalopathy syndrome
Objective: To describe the unusual clinical manifestations in a patient with posterior reversible encephalopathy syndrome. Background: Posterior reversible encephalopathy syndrome (PRES) is a transient clinical…Subthalamic neuromodulation restores motor learning in Parkinson’s disease
Objective: The aims of the present study were to (i) investigate the effect of subthalamic deep brain stimulation (STN-DBS) on motor learning in Parkinson’s disease…Dopaminergic neurons in Substantia Nigra pars compacta code the vigor of movement sequences
Objective: Assess the correlates of movement vigor in Substantia Nigra dopaminergic neurons Background: Current basal ganglia models have focused on the role of dopamine in…Neurostructural alterations associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson’s disease
Objective: The aim of current study was to evaluate the volumetry of subcortical structures in Parkinson's disease (PD) patients with Rapid Eye Movement (REM) Sleep…The relationship between asymmetric dopamine loss and cognition in early Parkinson’s disease patients from PPMI study
Objective: To explore the role of motor asymmetry on cognition in early stage Parkinson’s disease (PD). Background: PD is characterized by asymmetric motor onset which…Alteration to Basal Ganglia Morphology in Freezing of Gait in Parkinson’s Disease
Objective: To characterize the subcortical grey matter adaptations related to Freezing of Gait in Parkinson’s Disease (PD). Background: Owing to its connections with motor, cognitive…Does the Basal Ganglia Dysfunction Affect Pisa Syndrome in Parkinson’s Disease?
Objective: We elucidated whether and how asymmetric basal ganglia dysfunction is associated with the generation of Pisa syndrome (PS) in Parkinson’s disease (PD). To assess…Analysis of secondary causes in Fahr’s syndrome and whole exome sequencing in Fahr disease from Northeast China and South Korean
Objective: In this study, patients with Fahr syndrome were analyzed for etiology, and genetic testing was performed for patients with Fahr disease from Northeast China…Subthalamic theta oscillations in Parkinson’s disease
Objective: Identifying the effect of dopamine on subthalamic theta oscillations in Parkinson’s disease (PD). Background: Understanding the underlying electrophysiological alterations in PD is essential for…
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