Clinical Features Associated with Dysautonomia in Prodromal Parkinson’s Disease
Objective: To compare clinical features between those with and without dysautonomia in a cohort with other prodromal Parkinson’s disease (PPD) markers. Background: Dysautonomia has been…A qualitative evaluation of the health-related quality of life impact on informal caregivers to patients with neurogenic orthostatic hypotension
Objective: This study aimed to explore the impact of caring for an individual with neurogenic orthostatic hypotension (nOH) through qualitative interviews with informal caregivers and…Increased epinephrine in the saliva of Parkinson’s disease patients: A preliminary observation
Objective: To investigate the levels of dopamine (DA), norepinephrine (NE), epinephrine (EPI) and serotonin (5-HT) in the saliva of Parkinson’s disease (PD) patients and compare…Age and gender differences in cardiovascular autonomic failure in transgenic PLP-syn mouse model of multiple system atrophy
Objective: The main objective of the present study was to determine age and gender differences in measures of CAF in PLP-syn mice, a transgenic mouse…Subclinical cardiac autonomic dysfunction in patients with Parkinson’s disease: A pilot study
Objective: The aim of this study is to assess cardiac autonomic dysfunction in Parkinson’s disease (PD) patients. Background: Autonomic nervous system dysfunction (AD) is a…Intestinal transit in early-moderate Parkinson’s disease correlates with probable RBD – subclinical esophageal dysmotility does not correlate
Objective: To investigate esophageal and intestinal transit times in early-moderate Parkinson's disease (PD) and to study correlations with probable RBD and subjective symptoms. Background: Intraneuronal…Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy
Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…131-MIBG is less promising in differentiating Parkinson’s disease from other parkinsonism for early onset patients
Objective: To investigate the diagnostic value of 131I-MIBG cardiac scintigraphy in differentiating PD from other parkinsonism for distinct age of onset. Background: MIBG cardiac sympathetic imaging has…Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson’s disease
Objective: To characterize the gastrointestinal (GI) phenotype in the 6-hydroxydopamine (6OHDA) rat model of Parkinson’s disease (PD). Background: GI dysfunction, such as prolonged GI transit…Long-term changes in myocardial sympathetic innervation and function in synucleinopathies
Objective: Describe long-term trends in indices of cardiac sympathetic innervation and function in synucleinopathies. Background: A group of neurodegenerative diseases including Parkinson disease (PD), pure…