Real-life heart rate assessment: a digital biomarker for autonomic dysfunction in early Parkinson’s disease?
Objective: To assess whether 1) tremor and dyskinesia affect photoplethysmography (PPG) data quality, and 2) heart rate (HR) analysis based on continuous PPG can be…Clinical Prediction of GBA Carrier Status in Parkinson’s Disease
Objective: To design a model for prediction of GBA carrier status based on clinical and demographic features in a cohort of PD patients. Background: Given…Apathy in Parkinson’s disease: Relation to autonomic symptoms
Objective: Our overall goal was to learn whether apathy would be associated with autonomic symptoms in Parkinson’s disease (PD). We examined whether a) PD patients…Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD
Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…Sexual health and sleep quality in women living with Parkinson’s disease: are we neglecting that?
Objective: To investigate the relationship between sexual health and sleep quality in PD. Background: Sexual dysfunction (SD) is a common yet under-reported, non-motor symptom (NMS)…Orthostatic vital sign changes do not influence 5-year motor outcomes in PD
Objective: We assessed whether orthostatic blood pressure (BP) and heart rate (HR) changes in an early motor PD cohort influence motor, and postural instability and…Evidence of Central Autonomic Network dysfunction in orthostatic hypotension of Parkinson’s disease
Objective: To examine the contribution of the central autonomic network (CAN) to physiologic evidence of autonomic failure in Parkinson’s disease (PD). Background: Autonomic dysfunction, particularly…Levodopa-induced orthostatic hypotension in parkinsonism: a red flag of autonomic failure
Objective: To evaluate the cardiovascular and hemodynamic effect of LD in patients with parkinsonism on chronic LD treatment. Background: Levodopa (LD) is the main treatment…Pupil response is impaired in clinically isolated REM Sleep Behavior Disorder and Parkinsons’ Disease
Objective: Since easily accessible (bio-) markers are needed to predict progression and outcome in prodromal stages of neurodegenerative diseases this study was designed to evaluate…Resting heart rate variability in Parkinson’s disease with and without freezing of gait
Objective: The aim of the study was to investigate heart rate variability (HRV) in Parkinson’s disease (PD) patients with and without freezing of gait (FOG). Background: FOG and…
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