Apomorphine improves pulmonary function in parkinsonian patients
Objective: Aim of the study; to investigate if apomorphine might facilitate weaning from mechanical ventilation in parkinsonian patients. Background: Apomorphine is an effective treatment for PD…Sexual dysfunction precedes the classical motor symptoms of Parkinson’s disease?
Objective: To investigate whether sexual dysfunction precedes the classical motor symptoms of Parkinson’s disease. Background: There is growing evidence that some symptoms can precede the…Non-motor symptoms in Parkinson’s disease and the model of Braak
Objective: We aimed to determine different subtypes of Parkinson’s disease (PD) patients using clinical data from the appearance chronology of their non-motor and motor symptoms…Increased epinephrine in the saliva of Parkinson’s disease patients: A preliminary observation
Objective: To investigate the levels of dopamine (DA), norepinephrine (NE), epinephrine (EPI) and serotonin (5-HT) in the saliva of Parkinson’s disease (PD) patients and compare…Alterations of Blood Pressure Circadian Rhythm in Alpha-Synucleinopathies
Objective: To analyze the blood pressure (BP) circadian rhythm in Parkinson’s disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF), evaluating possible differences…A Comparative Study of Measured and Predicted Metrics of Respiratory Function in People with Parkinson’s Disease (PD)
Objective: The objective of this research was to compare measured metrics of respiratory function – Spirometry, Respiratory Muscle Strength and Peak Cough Flow – with…MIBG myocardial scintigraphy identifies premotor PD/DLB during a negative DAT scan period
Objective: It is unknown which marker is useful to identify the premotor phase PD/DLB. We recently reported four patients who, during a negative DAT scan…Changes in Supine Blood Pressure with Long Term Use of Droxidopa
Objective: To determine the long-term effects of droxidopa use on supine blood pressure (BP) in patients with neurogenic orthostatic hypotension (nOH). Background: nOH is a…The prevalence of supine hypertension and nocturnal hypertension and the difference of blood pressure in each sleep position in Parkinson’s disease
Objective: This study aimed to determine the prevalence, associated factors of SH/NH and to identify relationships between blood pressure (BP) and sleep position in PD…Population Pharmacokinetics and Pharmacodynamics of Ampreloxetine (TD-9855) in Patients with Neurogenic Orthostatic Hypotension (nOH)
Objective: To characterize the Phase 2 pharmacokinetics (PK) and pharmacodynamics (PD) of ampreloxetine in patients with nOH and provide dosing recommendations for special populations in…
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