Cognitive & Clinical Correlates of Quality of Life in Probable Progressive Supranuclear Palsy
Objective: To examine the relationship between cognitive, executive, motor & autonomic function, neuropsychiatric symptoms, and health-related quality of life (HRQoL) in patients with progressive supranuclear…Severe Gastroparesis and Atypical Parkinsonism as Presenting Features of Neuronal Intranuclear Inclusion Disease (NIID)
Objective: To report a case of adult-onset neuronal intranuclear inclusion disease (NIID) presenting with progressive gait instability, neurogenic bladder, and life-threatening gastrointestinal dysmotility. Background: NIID…The influence of probable rapid eye movement sleep behavior disorder on PD-related motor and non-motor symptoms and multiple functional outcomes among Chinese community-dwelling elderly population
Objective: To investigate associations of probable REM sleep behavior disorder (pRBD) with Parkinson's disease (PD)-related symptoms and functional outcomes in Chinese older adults. Background: The…Assessment of dysautonomia in patients with sporadic adult-onset ataxia
Objective: The aim of this study was to assess prevalence and severity of autonomic dysfunction in patients with SAOA, defined as a subacute or progressive…Longitudinal Changes and Clinical utility of the Neurological Pupillary Index in De Novo Parkinson’s Disease
Objective: To characterize longitudinal changes in pupillometric parameters in de novo Parkinson’s disease and explore their associations with clinical severity and disease progression. Background: Automated…Heart Rate Variability in Early Parkinson’s Disease
Objective: This study aimed to investigate the clinical relevance of heart rate variability (HRV), which may indicate underlying autonomic nervous system activity, in patients with…Testing the body vs brain-first hypothesis in early PD: a cross-sectional study
Objective: To assess whether body vs brain-first PD phenotypes differ in their autonomic, motor and non-motor burden in their early stages. Background: A growing body…Unveiling the unusual: PNMA2 paraneoplastic syndrome
Objective: To present a rare case report Background: A 69 year old woman presented with progressive ptosis, change in voice (hypophonia), dysphagia, generalised weakness with…The Parkinson’s Impact Project: A Multimodal Longitudinal Study of Disease Development and Progression at the 23andMe Research Institute
Objective: Characterize the interactions between lifestyle, environmental, and genetic exposures on susceptibility to Parkinson’s disease (PD) and progression rates through a scalable remote web-based multimodal…Standardized Autonomic and Movement Assessment in Mexican Patients with Undetermined and Degenerative Progressive Parkinsonism: A Single-Center Experience
Objective: We proposed a unified and standard autonomic and movement evaluation to discriminate patients' Parkinsonism related to synucleinopathies from other conditions during a clinical office…
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