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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Ataxia: Treatment"

  • MDS Virtual Congress 2020

    A translational approach to determine target concentrations of MIN-102 (leriglitazone) to support a Phase II study in Friedreich’s ataxia

    S. Poli, L. Rodríguez-Pascau, J. Ros, P. González-Cabo, E. Britti, D. Lynch, G. Pina, S. Pascual, M. Cerrada-Gimenez, D. Eckland, E. Traver, J. Wetering-de-Rooij, M. Martinell, U. Meya, P. Pizcueta (Gosselies, Belgium)

    Objective: To determine efficacious plasma concentration of leriglitazone from preclinical models of Friedreich´s ataxia (FRDA). To confirm CNS target engagement in a first-in human study.…
  • MDS Virtual Congress 2020

    Feasibility and Acceptability of Lee Silverman Voice Treatment for patients with hereditary ataxia

    A.N. Lowit, A. Egan, M. Hadjivassiliou (Glasgow, United Kingdom)

    Objective: This study aimed to assess the feasibility and acceptability of Lee Silverman Voice Treatment (LSVT) provided via Skype for patients with hereditary ataxia. Background:…
  • MDS Virtual Congress 2020

    Effects of deep transcranial magnetic stimulation of the cerebellum on cerebellar ataxias: A randomized, double-blind, cross-over clinical trial

    C. França, D. de Andrade, V. Silva, R. Galhardoni, E. Barbosa, M. Teixeira, R. Cury (Sao Paulo, Brazil)

    Objective: To investigate whether cerebellar deep repetitive transcranial magnetic stimulation (d-rTMS) can improve ataxic symptoms when compared to sham stimulation. Background: Cerebellar ataxia remains a…
  • MDS Virtual Congress 2020

    A randomized, sham-controlled, crossover trial on Cerebello-Spinal Transcranial pulsed current stimulation (tPCS) in Ataxia

    J. Ganguly, D. Kulshreshtha, S. Soltani, Y. Krishnasamy Tamilselvam, O. Samotus, D. Aur, M. Jog (London, ON, Canada)

    Objective: Patients of degenerative cerebellar ataxia present with slurring of speech, imbalance during walking and problem of co-ordination in limbs.  Currently no effective treatment is…
  • MDS Virtual Congress 2020

    Plasma biomarker quantification in SCA3 using the Neurology 4-PLEX A kit and the Simoa technology

    H. Garcia-Moreno, G. Thomas-Black, A. Heslegrave, H. Zetterberg, P. Giunti (London, United Kingdom)

    Objective: We present the results of plasma biomarker quantification in a cohort of spinocerebellar ataxia type-3 (SCA3) carriers using a Simoa assay. Background: Development of…
  • MDS Virtual Congress 2020

    Amantadine Therapy for Ataxia Management in Patients with Spinocerebellar Ataxia Type 7

    L. Pesantez Pacheco, N. Thakur (Houston, TX, USA)

    Objective: To report the therapeutic effects of amantadine in a patient with Spinocerebellar ataxia type 7 (SCA7) Background: Spinocerebellar ataxia type 7 is a rare…
  • 2019 International Congress

    Supportive treatments for Ataxia, a Randomized Control Trial

    MIA. Arain (Jamshoro, Pakistan)

    Objective: The objective of this study is to evaluate the effectiveness of supporting treatments that improve awareness and the quality of patient life and counsel…
  • 2019 International Congress

    Exergame training in Early Onset Ataxia patients

    R. Brandsma, I. Ganzevoort, M. Berg, ZT. Dominguez Vega, LD. Jelsma, MM. Schoemaker, NM. Maurits, CJC. Lamoth, DA. Sival (Groningen, Netherlands)

    Objective: In ambulant EOA children, we aimed to study the effect of a medically designed “ice-skating exergame” on balance, posture and muscle force parameters Background:…
  • 2019 International Congress

    Phosphodiesterase inhibitors as a treatment for Friedreich’s ataxia

    J. González-Fernández, E. Zucchet, P. Calap-Quintana, P. González Cabo, MD. Moltó Ruiz (València, Spain)

    Objective: To evaluate the effect of phosphodiesterase inhibitors, as potential treatment for Friedreich’s ataxia, in a Drosophila melanogaster model of the disease. Background: Friedreich’s ataxia…
  • 2019 International Congress

    Normative Reference for Timed Up and Go Test (TUG) in Young Indian Adults- Preliminary Results

    D. Kaur, K. Umakant, T. Aziz, P. Jaiswal, M. Kumari, A. Gupta, G. Kumar (Patna, India)

    Objective: This study investigated the clinical usefulness of the time up and go test in young population and provide a reference range for healthy adults.…
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