MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Ataxia: Pathophysiology"

  • 2025 International Congress

    Clinical and Dopaminergic Characteristics of MSA-C Patients with Predominant Cerebellar Asymmetry

    DG. Park, YS. Kim, YS. An, JH. Yoon (Suwon, Republic of Korea)

    Objective: To identify multiple system atrophy–cerebellar type (MSA-C) patients with marked cerebellar asymmetry and compare their features with symmetrically affected patients. Background: While asymmetry is…
  • 2025 International Congress

    Novel SPTAN1 Variant in Adult-Onset Cerebellar Ataxia in Active Duty Military Member

    M. Graham, J. Jacobson, L. Rohena (Fort Sam Houston, USA)

    Objective: The objective is to investigate the genetic basis of cerebellar ataxia and identify a novel variant associated with this condition in an active-duty military…
  • 2025 International Congress

    Adult-onset ataxia with oculomotor apraxia type 4 with severe hypoalbuminemia, generalized edema and obesity

    M. Paucar (Stockholm, Sweden)

    Objective: To report a 45-years-old Swedish man born to non-consanguineous parents affected by an adult-onset syndrome that included insidious pain at onset, hypoalbuminemia, edema, severe…
  • 2025 International Congress

    The FGF14-SCA27B GAA•TTC Repeat Shows Marked Somatic Expansion in the Cerebellum

    D. Pellerin, JL. Méreaux, S. Boluda, MC. Danzi, MJ. Dicaire, CS. Davoine, P. Iruzubieta, B. Hayward, D. Genis, G. Spurdens, JM. Hammond, BJ. Gerhart, M. Renaud, C. Bonnet, JS. Napierala, IW. Deveson, M. Napierala, K. Usdin, A. Brice, LM. Porcel, D. Seilhean, SL. Zuchner, H. Houlden, A. Durr, B. Brais (London, United Kingdom)

    Objective: To characterize somatic instability and molecular mechanisms of the FGF14 GAA•TTC repeat across serial blood samples, fibroblasts, induced pluripotent stem cells (iPSCs), and post-mortem brains. Background: Spinocerebellar…
  • 2025 International Congress

    Resting-state EEG analysis defines the signature of CACNA1A and GAA-FGF14 related channelopathies

    E. Indelicato, R. Angerbauer, I. Unterberger, M. Amprosi, W. Nachbauer, S. Boesch, M. Cesari (Innsbruck, Austria)

    Objective: The aim of this study was to investigate EEG metrics in patients with CACNA1A and GAA-FGF14 related diseases and to compare them with those…
  • 2024 International Congress

    Movement disorders in Brain Sagging Syndrome- A Systematic Review

    A. Datta, A. Lenka (Minneapolis, USA)

    Objective: Objective: This study aims to systematically review the array of movement disorders observed in patients diagnosed with brain sagging syndrome (BSS) secondary to spontaneous…
  • 2024 International Congress

    Fixel Analysis of Diffusion Imaging in Cerebellar Tracts as a Quantitative Marker of Disease Progression in Spinocerebellar Ataxia

    D. Arpin, S. Subramony, D. Vaillancourt, M. Burns (Gainesville, USA)

    Objective: This study aimed to identify white matter changes in the brain of presymptomatic and early-stage SCA1 and SCA3 mutation carriers using fixel-based analysis of…
  • 2024 International Congress

    Two-year longitudinal evaluation of ataxia and brain structural changes in RFC1-related disorder

    C. Lobo, T. Rezende, G. Schmitt, P. Matos, F. Lima, A. Martinez, O. Barsottini, JL. Pedroso, W. Marques Jr, M. França Jr (Campinas, Brazil)

    Objective: To describe the evolutionary pattern of brain structural changes in patients with RFC1-related disorder. Background: Specific brain structural changes have been described in patients…
  • 2024 International Congress

    Autosomal recessive spastic ataxia of Charlevoix–Saguenay: Case report with 3 family members affected.

    H. Pacheco Mendoza, L. Nuñez Orozco, P. Briseño López, A. Negrete Gómez, J. Delgado Uriarte (Mexico, Mexico)

    Objective: Report a case of ARSACS in a patient with 2 siblings also affected Background: Autosomal recessive spastic ataxia of Charlevoix–Saguenay (ARSACS) is a rare…
  • 2023 International Congress

    Systemic and intracellular iron starvation response in Friedreich´s Ataxia

    E. Indelicato, M. Amprosi, A. Eigentler, W. Nachbauer, D. Haschka, M. Grander, B. Henninger, C. Kremser, G. Weiss, S. Boesch (Innsbruck, Austria)

    Objective: To investigate the hepcidin-ferroportin mediated iron metabolism regulation in Friedreich´s Ataxia (FA). Background: FA is a devastating neurogenetic disorder caused by biallelic GAA expansions…
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