Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the raphe nuclei
Objective: To investigate whether apathy is related to serotonin depletion in the raphe nuclei in patients with rapid eye movement sleep behaviour disorder (RBD), a…Depression, apathy, fatigue in Parkinson with or without STN DBS
Objective: To determine the prevalence of depression, evaluate the relationship between depression, apathy and fatigue, and the impact of STN DBS on the same symptoms.…Perry syndrome: Proposal of international diagnostic criteria and a new disease concept
Objective: To propose international diagnostic criteria for Perry syndrome and a new disease concept. Background: Perry syndrome is a rare autosomal dominant neurodegenerative disease characterised…Impact of SYN120 (a Dual 5-HT6/5-HT2A antagonist) on psychiatric symptoms in patients with Parkinson’s disease dementia: Results from a Phase 2a Study
Objective: To assess the psychiatric effects of SYN120 in patients with Parkinson's disease dementia (PDD). Background: SYN120 is a dual antagonist of serotonin (5-HT6 and…Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…Apathy in adolescents with Tourette syndrome (TS), more than a teenager attitude
Objective: To explore the presence of apathy in teenagers with TS. Background: TS is a complex neuropsychiatric disorder generally classified as a hyperkinetic disorder. Apathy…Relationship between the MDS-UPDRS and quality of life in Parkinson’s disease: A large international multicenter study of 3206 patients (the QUALPD study)
Objective: To evaluate the relationship between the International Parkinson and Movement Disorder Society – Unified Parkinson's disease Rating Scale (MDS-UPDRS) and Quality of Life (QoL)…Relationships of cognitive functions and psychiatric symptoms with motor phenotypes in patients with untreated early-stage Parkinson’s disease
Objective: It has been shown that the clinical types of Parkinson's disease (PD) based on motor symptoms include motor phenotypes of postural instability and gait…
- « Previous Page
- 1
- …
- 5
- 6
- 7
- 8
- 9
- Next Page »