Does hyposmia induce apathy in early Parkinson’s disease? Lessons from structural brain connectivity
Objective: To study changes in microstructural integrity of white matter tracts associated with apathy in patients with early Parkinson’s disease (PD) and hyposmia Background: Smells…Effects of Motor Subtype Stability on Non-Motor Symptoms in Early Parkinson’s Disease
Objective: To determine the effects of motor subtypes’ stability on non-motor symptoms (NMS) over three years in early Parkinson’s disease (PD). Background: Research have found…Effort-based decision-making and neuropsychiatric symptoms before and after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: Parkinson’s disease patients with apathy and patients in the medication OFF state show reduced reward sensitivity in effort-based decision-making tasks. The effect of subthalamic…Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease
Objective: To investigate whether changes in connectivity between neural regions that are associated with goal-directed behaviour predict future development of apathy in people with Parkinson’s…Apathy and impulsivity co-occur in Huntington’s disease
Objective: To determine whether apathy and impulsivity co-occur in people with Huntington’s disease. Background: Apathy and impulsivity are debilitating behavioural changes which often occur in…Identifying neural biomarkers of motivated behavior in Parkinson’s disease using sensing-capable DBS devices
Objective: To investigate neural correlates of motivated, goal directed behavior within the basal ganglia. Background: Apathy is a common and debilitating complication of Parkinson’s disease…Failure of model-based outcome monitoring in Parkinson’s Disease Apathy
Objective: To investigate the neural basis of apathy in Parkinson’s Disease (PD). Background: Apathy is a debilitating and poorly understood syndrome characterised by a reduction…Apathy correlated with motor and non-symptoms in de-novo patients with Parkinson’s disease
Objective: We aimed to investigate how the severity of apathy affects motor symptom and other non-motor symptoms in patients with de-novo Parkinson’s disease (PD). Background:…Apathy in Parkinson’s disease: Relation to autonomic symptoms
Objective: Our overall goal was to learn whether apathy would be associated with autonomic symptoms in Parkinson’s disease (PD). We examined whether a) PD patients…Temporal dynamics and longitudinal predictors of apathy in Parkinson’s disease
Objective: To determine how apathy varies across different disease stages of Parkinson’s disease (PD) and the longitudinal predictors of its development, using a large PD…
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