1H-NMR and UPLC/MS Metabolomics Identify Disrupted Homeostasis of Energy, Amino Acids, and Glutathione Metabolism as Serum Signatures in Parkinson’s Disease Patients
Objective: We sought to identify a signature distinctive of Parkinson’s disease (PD) through two independent metabolomics approaches. Background: A recent meta-analysis showed a considerable inconsistency…Gait Improvement in Pegzilarginase-treated Patients With Arginase 1 Deficiency: A Blinded Kinematic Analysis
Objective: To assess the impact of pegzilarginase therapy on gait kinematics in Arginase 1 Deficiency (ARG1-D) patients. Background: High arginine levels in patients with ARG1-D…Motor and non-motor correlates of APOE-ε4 mediated cerebrospinal fluid concentrations of amino acids and monoamine metabolites in dementia with Lewy bodies compared with Alzheimer’s dementia and healthy controls
Objective: To study associations of cerebrospinal fluid (CSF) amino acids and monoamine metabolites with motor and non-motor features in dementia with Lewy bodies (DLB) compared…Cyclic glycine-proline increased in the cerebrospinal fluid of Parkinson’s patients after supplementation of blackcurrant anthocyanins: Potential biomarker for treatment
Objective: We evaluated the changes of insulin-like growth factor-1 bioavailability in the Parkinson's disease patients after 28 day supplementation of blackcurrant anthocyanin. Background: Elevated insulin-like…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.