Morphometric assessment of age-associated neuronal changes in the human locus coeruleus
Objective: To delineate the age-related changes in the neuronal size and neuromelanin (NM) intensity in autopsied tissues of human locus coeruleus (LC). Background: Many studies…Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…Comparison in the disability level according to WHODAS 2 between people living with Early and Late Onset Parkinson’s Disease
Objective: To compare disability levels according to WHODAS-2 between people living with EOPD and people living with LOPD. Background: Although Parkinson's disease (PD) is more…The incidence of Parkinson’s disease in Nigeria: a systematic review and meta-analysis
Objective: The study aim to integrate various investigations pertaining to the incidence of Parkinson's disease (PD) in Nigeria, with the objective of comprehensively characterizing the…Applying the COM-B model to identify potential barriers for in-person on-site visits within the Healthy Brain Ageing (HeBA) study in Luxembourg
Objective: This study aims to (1) apply the Capability, Opportunity, and Motivation model of Behaviour (COM-B) to the HeBA online survey to identify potential barriers that could…Establishing and validating 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced zebrafish model of Parkinson’s disease
Objective: The current study aims to establish a zebrafish model of PD using MPTP neurotoxin and the validation of the MPTP effect through swimming behavior…Clinical and risk profiles of Parkinson’s disease from a large pan-India cohort: interim observations of the GAP-India study
Objective: To create a pan-Indian clinical repository of Parkinson’s Disease (PD). Background: The genetic risk for PD in India is unknown. The Luxembourg-German India Alliance…Demographic and Regional Variation in All-Cause Mortality Rates among United States Medicare Beneficiaries with Parkinson’s Disease
Objective: To determine whether all-cause mortality rates among persons with Parkinson’s disease (PD) in the United States (US) differ by sex, race/ethnicity, or geographic location.…Exploring Young people’s role in providing relief to grandparents affected with Alzheimer
Objective: In some families, children never know that their parents or grandparents are affected by the Parkinson’s Disease (PD). Whatever be the way that Movement…Metabolic Biomarkers of Parkinson’s Disease in Peripheral Tissue
Objective: The goal of this study was to use magnetic resonance spectroscopy (MRS) to test whether muscles of individuals with Parkinson’s disease (PD) possess a…
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