Rora deficiency aggravates dopamine neurons loss via reducing NAD+ level in Parkinson’s disease
Objective: To investigate the mechanism by which retinoic acid-related orphan receptor alpha(RORα) regulates NAD+ levels to dopamine neuronal degeneration in Parkinson’s Disease (PD). Background: PD is an age-related degenerative…Simulated Space Gravity Recapitulates Parkinson’s Disease Pathology in Neural Cell Model
Objective: This investigation centers on the potential influence of microgravity on α-synuclein aggregation, a hallmark feature of Parkinson's disease (PD) characterized by the formation of…Age- and Sex-Associated Changes in the Behavior of Neuronal Mitochondria During Healthy Aging
Objective: To determine age-associated changes in the size, density, movement, and dynamics of mitochondria as a function of sex, using microRNA-induced neurons derived from primary…Cortical activity during visually perturbed gait in older adults
Objective: The primary aim of this preliminary study was to explore pre-frontal cortex (PFC) and posterior parietal cortex (PPC) activity in older adults (OAs) during…Use of social media and health information technology among caregivers of Alzheimer’s disease and other neurological conditions: Secondary analysis of the 2022 Health Information National Trend (HINTS) Survey
Objective: This study aims to evaluate the pattern of health information seeking from social media and other health technology tools among caregivers for individuals with…Age-associated Changes in Microglial Morphology and its Role in Deciphering Susceptibility to Parkinson’s Disease
Objective: To delineate the age-associated changes in microglial morphotypes in the substantia nigra pars compacta (SNpc) of C57BL/6J and CD-1 mice and alterations in response…Association between use of Furosemide and Risk of Parkinson’s disease
Objective: Main objective of study is to check the association between furosemide use and risk of Parkinson's disease (PD) in a Finnish nationwide nested case-control…A pathology-validated study to investigate the role of Uric Acid in Parkinson’s Disease
Objective: The aim of this study is to compare plasma uric acid levels between pathology-confirmed and clinically misdiagnosed Parkinson’s disease patients at a single-patient level.…Dual-Task Cost of Walking While Using a Smartphone: A Comparison Study of Older Adults with and Without Cognitive Decline
Objective: To investigate spatiotemporal gait parameters in older adults with and without cognitive decline while walking in the presence of smartphone use. Background: The use…Vegetables and fruits to relieve constipation: Do Parkinson’s disease patients know them?
Objective: To compare the knowledge of vegetables and fruits for treating constipation between PD and non-PD patients with constipation. Background: Constipation is a common non-motor…
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