A Post-mortem Study on Striatal Glia and Blood Brain Barrier Integrity in Aging and PD Asian-Indians.
Objective: We examined the glial and blood brain barrier (BBB) changes related to normal aging and PD in the Asian-Indian striatum. Background: increases the risk…PD in Tanzania: representative in city dwellers, absent in nomadic tribespeople?
Objective: To investigate the aetiology of PD demographically in an under researched region. Background: PD monogenic and susceptibility risk factors explain little to none of…Evaluation of Neurotransmitter and Co-transmitter Expression in the Aging Human Locus Coeruleus: Relevance to Neurodegenerative Disorders.
Objective: To analyze the age-associated changes in the neurotransmitter/co-transmitter expression and morphometric profiles of human locus coeruleus (LC) neurons using autopsied human tissues. Background: LC…Exploring the Feasibility of Telerehabilitation for Balance Deficits in People with PD; the TelePD Trial
Objective: To evaluate the feasibility of adapting our Agility Boot Camp (ABC) for balance telerehabilitation (Tele-ABC) in people with mild-to-moderate Parkinson’s disease (PD). Background: Balance impairments…A Study of Age-related Changes in Galanin Expression in the Neuropil and Associated Boutons in the Human Locus Coeruleus.
Objective: To determine the age-effects on galanin (Gal)-enriched synaptic boutons and neuropil of human locus coeruleus (LC) using autopsied human tissues. Background: The LC has…Long-term Physical Exercise on Bone Mineral Density, Balance and Gait in Older Adults with Mild to Moderate Parkinson’s Disease
Objective: To determine the effects of a long-term exercise program on bone health, balance and gait in older adults with mild to moderate Parkinson's disease…Possible Sarcopenia and its Association with Physical Activity among Parkinson’s disease Patients
Objective: This study aimed to screen the prevalence of possible sarcopenia and its association with physical activity level in a sample of PD patients. Background:…The AIMS Clinic Model: A Retrospective Analysis of Interdisciplinary Neuropalliative Care for People with Advanced Parkinsonism
Objective: To describe and evaluate the Advanced Interdisciplinary Movement Disorders Supportive Care (AIMS) Clinic, a novel interdisciplinary clinic for patients with advanced movement disorders. Background:…Experiences of a personalised intervention to support self-management in PwP – PD-Care: Live Well with Parkinson’s
Objective: 1) Evaluate acceptability and feasibility of the intervention2) Understand barriers and enablers to engagement and intervention improvement recommendations Background: We co-designed the ‘Live Well…Benefits of Exercise on Mobility, Balance, and Cognition in Community-Dwelling Older Adults: An On-Land vs. In-Water Comparison Study
Objective: We conducted a three-arm trial (water exercise group × land exercise group × no exercise group) to assess the effects of a 4-month exercise…
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