Loss of VPS29 disrupts retromer function and synaptic transmission, leading to neurodegeneration in Drosophila
Objective: To understand the role of the retromer complex in the central nervous system(CNS), and its link to Parkinson's disease (PD) susceptibility. Background: Mutations in…Analyses of physical activity on cognitive flexibility, depression and RBD in healthy elderly with high risk for neurodegenerative diseases
Objective: In this study we set out to evaluate the effect of physical activity on cognition, fine motor movements and axial motor parameters in a…General Anesthesia and Parkinson’s Disease
Objective: Postoperative cognitive dysfunction is common among the elderly. These changes may even be so severe that some elderly people actually become demented after undergoing…Motor and non-motor symptoms in old-age onset Parkinson’s Disease patients
Objective: Understand the role of old-age onset in Parkinson’s Disease (PD) motor and non-motor phenotype. Background: Advancing age is a risk factor for PD. With…Parkinsonism in the very old – A clinicopathological study
Objective: To identify, spectrum of Parkinson variants, clinical features and course of disease in age > 80 year onset cases. Background: Old age is the…Beneficial and Protective Effects of Withania Someniferais On Mice Brain: A Therapeutic Potential Drug for Parkinson’s Disease
Objective: Objective of our study was evaluate effect of Withania Someniferais leaves on Parkinsons brain of mice Background: Parkinson’s disease (PD), an age-related disorder, is…Salivary Alpha-Synuclein in Aging
Objective: We measured alpha-synuclein total (a-syntotal) and alpha-synuclein oligomers (a-synolig) concentration in 70 healthy subjects, of different ages (from 18 to 88 years old) to…Association of arterial stiffness with cognition in patients with Lewy body disorder
Objective: We aimed to investigate the association between arterial stiffness and cognitive function in patients with Lewy body disorder (LBD), including Parkinson disease (PD) and…Using eye tracking to identify pupil and saccade biomarkers of neurodegenerative disease
Objective: The Ontario Neurodegeneration Research Initiative Program (1) is investigating patients with neurodegeneration (Alzheimer’s disease: AD; mild cognitive impairment: MCI; Parkinson’s disease: PD; amyotrophic lateral…Information Content of Spoken Language in Parkinson’s Disease Without Dementia
Objective: Investigate differences in spoken language content in Parkinson’s disease (PD) compared to older controls. Background: Conveying information is a primary goal of communication. PD language…
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