Increased hub function in posterior medial cortex in Parkinson’s disease without mild cognitive impairement – A resting state fMRI study –
Objective: Using resting-state functional MRI (rsfMRI) data of younger and older healthy volunteers and patients with Parkinson’s disease (PD) with and without mild cognitive impairment…Normative Curves for Selected Unified Huntington Disease Rating Scale Measures
Objective: To examine the effects of natural aging for those without Huntington disease (HD) gene expansion and to develop normative curves by age, sex, and…Drug Utilization in a Real World Cohort with Progressive Supranuclear Palsy
Objective: To evaluate the frequency of prescription medications commonly associated with the management of PSP in the community. Background: Progressive Supranuclear Palsy (PSP) is a…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…The Efficacy and Safety of Gocovri Based on Age: Special Population Analyses of a Phase 3 Study Program
Objective: To assess patient outcomes and adverse events in Parkinson’s disease (PD) patients treated with Gocovri® (amantadine) extended release capsules at bedtime for dyskinesia, by…Validation of the PREDIGT Score for the Incidence Rate of Parkinson disease
Objective: To assess the discriminative power of the PREDIGT formula for incident Parkinson disease (PD). Background: The inability to predict the incidence rate of PD…Amyloid load and cognitive decline in Parkinson’s disease: preliminary longitudinal findings
Objective: To test for any association between amyloid deposition and future cognition in Parkinson’s disease, in a sample enriched for mild cognitive impairment. Background: Progressive…Clinico-pathological Findings In Autopsy Cases With Non-Specific Glial Tauopathy
Objective: Determine Clinico-pathological correlates of aging-related tau astrogliopathy (ARTAG). Background: Aging-related tau astrogliopathy (ARTAG) appears to be a morphological spectrum of astroglial pathology mostly seen in…Risk of Parkinson’s in idiopathic anosmia
Objective: To identify markers of increased risk of Parkinson’s in a cohort of individuals with idiopathic anosmia Background: Smell loss (anosmia) is a common finding…In vivo and In vitro study of 17β estradiol against amyloid beta neurotoxicity in synaptosomes of aging female rats : A therapeutic potential drug for Alzheimer’s disease
Objective: The aim of the present study was to determine the effects of neuropeptide, neurokinin B (NKB) and amyloid beta fragment Aβ (25-35) on 17β…
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