Experiences of a personalised intervention to support self-management in PwP – PD-Care: Live Well with Parkinson’s
Objective: 1) Evaluate acceptability and feasibility of the intervention2) Understand barriers and enablers to engagement and intervention improvement recommendations Background: We co-designed the ‘Live Well…Benefits of Exercise on Mobility, Balance, and Cognition in Community-Dwelling Older Adults: An On-Land vs. In-Water Comparison Study
Objective: We conducted a three-arm trial (water exercise group × land exercise group × no exercise group) to assess the effects of a 4-month exercise…Rora deficiency aggravates dopamine neurons loss via reducing NAD+ level in Parkinson’s disease
Objective: To investigate the mechanism by which retinoic acid-related orphan receptor alpha(RORα) regulates NAD+ levels to dopamine neuronal degeneration in Parkinson’s Disease (PD). Background: PD is an age-related degenerative…Simulated Space Gravity Recapitulates Parkinson’s Disease Pathology in Neural Cell Model
Objective: This investigation centers on the potential influence of microgravity on α-synuclein aggregation, a hallmark feature of Parkinson's disease (PD) characterized by the formation of…Age- and Sex-Associated Changes in the Behavior of Neuronal Mitochondria During Healthy Aging
Objective: To determine age-associated changes in the size, density, movement, and dynamics of mitochondria as a function of sex, using microRNA-induced neurons derived from primary…Cortical activity during visually perturbed gait in older adults
Objective: The primary aim of this preliminary study was to explore pre-frontal cortex (PFC) and posterior parietal cortex (PPC) activity in older adults (OAs) during…Use of social media and health information technology among caregivers of Alzheimer’s disease and other neurological conditions: Secondary analysis of the 2022 Health Information National Trend (HINTS) Survey
Objective: This study aims to evaluate the pattern of health information seeking from social media and other health technology tools among caregivers for individuals with…Association between use of Furosemide and Risk of Parkinson’s disease
Objective: Main objective of study is to check the association between furosemide use and risk of Parkinson's disease (PD) in a Finnish nationwide nested case-control…Age-associated Changes in Microglial Morphology and its Role in Deciphering Susceptibility to Parkinson’s Disease
Objective: To delineate the age-associated changes in microglial morphotypes in the substantia nigra pars compacta (SNpc) of C57BL/6J and CD-1 mice and alterations in response…Dual-Task Cost of Walking While Using a Smartphone: A Comparison Study of Older Adults with and Without Cognitive Decline
Objective: To investigate spatiotemporal gait parameters in older adults with and without cognitive decline while walking in the presence of smartphone use. Background: The use…
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