MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Acetylcholine"

  • MDS Virtual Congress 2020

    Compared the effects of probiotics and Anti-PD particles on the behavior of Parkinson’s disease mice model

    X.H Zhao, Y.B Wang, J. Yang, L.Y Zhang, H.Q Liu, H.J Sui (Shanghai, China)

    Objective: To compared the effects of probiotics and Anti-PD particles on the behavior of mice with MPTP Parkinson's disease (PD) model. Background: Intestinal flora may…
  • MDS Virtual Congress 2020

    Decreased Regional Cholinergic Signaling in Parkinson’s Disease

    J. O'Donnell, Y. Zhou, M. Campbell, S. Mansor, B. Maiti, Z. Tu, J. Perlmutter (Saint Louis, MO, USA)

    Objective: To identify regions of decreased cholinergic signaling in Parkinson's disease (PD) participants relative to cognitively normal controls as measured by positron emission tomography imaging…
  • MDS Virtual Congress 2020

    Early cognitive impairment is associated with specific regional cholinergic denervation in Parkinson’s disease

    S. vander Zee, J. Boertien, M. Gerritsen, J. Spikman, T. van Laar (Groningen, Netherlands)

    Objective: To evaluate regional cholinergic correlates of cognitive impairment in newly diagnosed, treatment-naïve Parkinson’s disease (PD) patients. Background: Mild cognitive impairment (PD-MCI) is a common…
  • MDS Virtual Congress 2020

    Clinical and neurological features of the course of parkinsonism in the presence of chronic renal disease

    S. Khudayarova, G. Rakhmatullaeva (Tashkent, Uzbekistan)

    Objective: To study the clinical and neurological features of the course of parkinsonism in chronic renal disease. Background: Under our supervision were 30 patients with…
  • MDS Virtual Congress 2020

    Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study

    K. Baik, S. Kim, S. Kang, Y. Sohn, P. Lee, S. Kang (Seoul, Republic of Korea)

    Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…
  • 2019 International Congress

    Non-Invasive Vagus Nerve Stimulation: A non-pharmacological approach to target gait impairment in Parkinson’s disease?

    A. Yarnall, R. Morris, H. Hunter, JP. Taylor, M. Baker, L. Rochester (Newcastle Upon Tyne, United Kingdom)

    Objective: To determine whether single dose non-invasive vagus nerve stimulation (nVNS) enhances gait performance in Parkinson’s (PD). Background: Loss of cholinergic neurons from nucleus basalis…
  • 2019 International Congress

    Neuroprotective and neurotrophic efficacy of Ginkgo biloba extracts against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease

    P. Kashyap, S. Gupta (Darbhanga, India)

    Objective: The present study examined the potential neuroprotective and neurotrophic efficacy of GBE against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD…
  • 2019 International Congress

    Contribution of pedunculopontine nucleus cholinergic neurons to L-DOPA-induced dyskinesia and PD motor deficits in hemi-parkinsonian rats

    N. Chambers, J. Sergio, C. Saito, K. Lanza, C. Bishop (Binghamton, NY, USA)

    Objective: To determine if chemogenetic and pharmacological modulation of pedunculopontine nucleus (PPN) cholinergic neurons can alter L-DOPA-induced dyskinesia and gait deficits in hemi-parkinsonian rats. Background:…
  • 2019 International Congress

    Role of APOE ε4 status and Sex on Somatosensory Integration and Dual-Task Cost in Parkinson’s disease

    D. Martini, R. Morris, G. Mcbarron, T. Madhyastha, T. Grabowski, SC. Hu, C. Zabetian, A. Hiller, K. Chung, J. Quinn, F. Horak (Portland, OR, USA)

    Objective: To determine whether ε4 status relates to impaired somatosensory integration deficits in males more than females in people with Parkinson’s disease (PwPD). Background: Previous…
  • 2019 International Congress

    A case of donepezil-induced multifocal myoclonus

    C. Amlang, P. Kim, A. Padalia, B. Roy, S. Schaefer (New Haven, CT, USA)

    Objective: To describe the case of a patient who developed severe multifocal myoclonus due to donepezil. Background: Donepezil is a cholinesterase inhibitor frequently used to…
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