2024 International Congress » Parkinson's Disease: Neuroimaging

Meeting: 2024 International Congress

[18F]PR04.MZ PET CT as a clinical tool in the differential diagnosis of PD and other atypical parkinsonian syndromes in the first 5 years of symptoms

C. Montalva, M. Sanchez, J. Fuentes, P. Chana, P. Salles, V. Kramer, X. Pizarro (Santiago, Chile)

A Kinematic and fMRI Study of the Neural Correlates of Bradykinesia in Parkinson’s Disease

E. Sarasso, A. Gardoni, L. Zenere, D. Emedoli, R. Balestrino, A. Grassi, S. Basaia, C. Tripodi, E. Canu, M. Malcangi, E. Pelosin, MA. Volontè, D. Corbetta, M. Filippi, F. Agosta (Milan, Italy)

Abnormal basal ganglia-related functional gradient in Parkinson’s disease

L. Chen, L. Sun, M. Xia, T. Wu (Beijing, China)

Accuracy of AI-driven automated diagnostic software analyzing Susceptibility Map-Weighted Imaging to Differentiate Neurodegenerative from Non-neurodegenerative Parkinsonism

E. Wallert, E. V.D. Giessen, M. Beudel, T. van Mierlo, J. Blankevoort, DH. Shin, R. de Bie, J. Booij (Amsterdam, Netherlands)

AI based longitudinal changes in substantia nigra contrast and volume on neuromelanin MRI and its relation to clinical markers in a multi-site Parkinson’s disease study.

M. Ingalhalikar, H. Pham, T. G, L. Bracoud, MH. Hutchison, K. Evans, T. Dam, KN. Nguyen, CC. Conklin, JS. Suhy, DS. Scott (San Mateo, USA)

Alterations in neural processes of cognitive control in asymptomatic heterozygous mutation carriers in the Parkin gene

J. Böhm, J. Uter, R. Lundin, J. Henkel, P. Pramstaller, C. Klein, A. Hicks, M. Heldmann, N. Brüggemann (Lübeck, Germany)

Altered Dynamic Functional Connectivity in Parkinson’s Disease Individuals with Visual Hallucinations and Dysfunction

MA. Alizadeh, SN. Naghizadehkashani, OS. Shoraka, KS. Shivok, IF. Fayed, KH. Hines, AA. Atik, CM. Matias, RS. Sergott, TWL. Liang, CW. Wu (Philadelphia, USA)

Analysis of structural connectivity in relation to change in dopaminergic medication after 6 months of STN-DBS in Parkinson´s disease – a pilot study

š. Janovič, D. Kroneberg, B. Al-Fatly, A. Kušnírová, Z. Košutzká (Bratislava, Slovakia)

Assessment of Visual Field in Patients with Moderate-to-Severe Parkinson’s Disease

S. Mehta, M. Syed, S. Naghizadehkashani, K. Shivok, L. Krisa, C. Matias, C. Wu, T. Liang, R. Sergott, M. Alizadeh (Philadelphia, USA)

Association Between Cerebral Glucose Metabolism and Amyloid Deposition in Parkinson’s Disease

HK. Na, Y. Sun, JH. Lee, CW. Park, YH. Sohn, CH. Lyoo, PH. Lee (Seoul, Republic of Korea)

Association of Striatal Dopaminergic Depletion, Cerebral Perfusion, and Cognitive Outcome in Brain-first and Body-first Parkinson’s Disease

SH. Jeong, JS. Baik, PH. Lee, SJ. Chung (Seoul, Republic of Korea)

Associations between Choroid Plexus and tau in Parkinson’s Disease

Z. Wang, J. Li, C. Cai, C. Jiang, L. Zhao (Hangzhou, China)

Associations Between Striatal Dopamine Transporter Binding and Motor Asymmetry In De Novo PD with and Without RBD

H. Hameed, S. Elasfar, K. Ehgoetz Martens (Waterloo, Canada)

Automated Imaging Differentiation of Parkinsonism (AIDP): A Prospective 21-site Trial within the Parkinson’s Study Group

D. Vaillancourt, A. Barmpoutis, R. Chen, J. Desimone, M. Schauder, W. Wang, T. Parish, R. Fang, M. Okun (Gainesville, USA)

Cardiac Mitochondrial Complex I Integrity Predicts Axial Symptom Severity in Parkinson’s Disease

S. Roytman, G. Carli, R. Vangel, P. Kanel, R. Koeppe, N. Bohnen (Ann Arbor, USA)

Cerebral metabolic network in PLA2G6-associated parkinsonism

XY. Zhou, J. Wang, C. Chen, FT. Liu, CT. Zuo, JJ. Wu, YM. Sun, J. Wang (Shanghai, China)

Cerebral vasoreactivity in patients with Parkinson’s disease and Diabetes Mellitus

A. Martínez-Rodríguez, M. Cansino-Torres, D. Ortiz-Zacarias, S. Castillo-Torres, F. Góngora-Rivera, B. Chávez-Luévanos, I. Estrada-Bellmann (Monterrey, Mexico)

Cerebrovascular Reactivity and Glymphatic Clearance in Parkinson’s disease

S. Ryman, E. Erhardt, N. Shaff, A. Dodd, N. Hoffman, S. Nitschke, K. Julio, G. Suarez-Cedeno, A. Deligtisch, D. Sugar, H. Lin, A. Vakhtin, HJ. Van-Der-Horn, S. Pirio Richardson, A. Mayer (Albuquerque, USA)

Characterization of a Novel alpha-synuclein PET radiotracer, [18F]C05-05, in a PPMI Sub-study

D. Russell, C. Constantinescu, R. Gunn, J. Eberling, A. Lorenzo, M. Rowland, S. Roman, J. Seibyl, K. Marek, MJF. Imaging Consortium, THE. Ppmi Study (New Haven, USA)

Characterizing levodopa-induced dyskinesias using multimodal neuroimaging, clinical and behavioral measures

S. Shukla, S. Tinaz, N. Thirugnanasambandam (Mumbai, India)

Cholinergic Basal Forebrain Integrity and Cognition in Parkinson’s Disease

N. Slater, T. Melzer, D. Myall, G. Hall-Mcmaster, A. Harris, K-L. Horne, T. Anderson, J. Dalrymple-Alford (Christchurch, New Zealand)

Cholinergic brain vulnerabilities associate with diabetic comorbidity in Parkinson disease

G. Carli, P. Kanel, T. Brown, S. Roytman, R. Albin, N. Bohnen (Ann Arbor, USA)

Classification of Parkinson’s disease using AI based on multi-modal brain MRI connectomics

T. Teo, T. Welton (Singapore, Singapore)

Clinical and Brain Morphological Characteristics of Early LRRK2-associated Parkinson Disease

Q. Tao, S. Rahayel, C. Tremblay, A. Vo, A. Dagher (Montreal, Canada)

Comparative Study of Whole-Brain Functional Connectivity Patterns in Parkinson’s Disease and Essential Tremor: A Resting-State fMRI Study

O. Shoraka, S. Naghizadeh Kashani, M. Syed, K. Shivok, T. Liang, R. Sergott, I. Fayed, C. Matias, C. Wu, A. Sharan, M. Alizadeh (Philadelphia, USA)

Comparing 18F-AV133 VMAT2 PET and DATscan as Markers of Parkinson’s Disease Severity and Progression

M. Miyasaka, A. Avbersek, M. Ahmed, M. Effendi, O. Harari, L. Pham, S. Somersan-Karakaya, L. Sun, O. Levy, F. Sepehrband (Tarrytown, USA)

Comparison of Spontaneous Brain Activity in Distinguishing Parkinsonian Variant of Multiple System Atrophy from Parkinson’s Disease at Early Stage

S. Wang, Y. Xiao, Y. Hou, C. Li, L. Zhang, R. Ou, Q. Wei, J. Lin, T. Yang, N. Che, Q. Jiang, X. Zheng, J. Liu, H. Shang (Chengdu, China)

Connectivity Profile for Increased Apathy Following Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease

E. Abdou, K. Pazira, S. Sharp, J. Summers, K. Dhima, M. Hacker (Nashville, USA)

Cortical morphometry and subcortical volumetry in motor subtypes of Parkinson’s disease

P. Pal, S. Prasad, T. Nagaraj, S. Bhat, S. Purushotham, R. Taneja, V. Holla, R. Mahale, N. Kamble, R. Yadav, J. Saini (Bengaluru, India)

Data-driven image-based subtyping and staging of neurodegeneration in Parkinson’s disease

J. Ha, G. Park, JS. Lee, JH. Ahn, W. Kim, JW. Cho, H. Kim, J. Youn (Seoul, Republic of Korea)

Decrease in Walking Ability with Increased Functional Connectivity between Multiple Brain Areas in Parkinson’s Disease

ZZ. Zhu, JL. Wu, NB. Yu, JD. Han, J. Wang, Y. Wang (tianjin, China)

Deep learning-based Prediction of Gait Dysfunction in Parkinson’s Disease using Quantitative Diffusion MRI from Brain Network Regions of Interest

C. Raimondo, L. Singanamala, M. Alizadeh (Philadelphia, USA)

Differences in regional activity levels between healthy controls, PD-nFOG, and PD-FOG as measured by ALFF and fALFF using resting-state fMRI.

T. Davis, Z. Mari, V. Mishra (Birmingham, USA)

Differential Diagnosis of Parkinsonism with 18F-FP-CIT PET using a Self-supervised Deep Learning Model

GY. Lee, J. Won, S. Jo, J. Lee, S. Lee, N. Kim, SJ. Chung (Seoul, Republic of Korea)

Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease

V. Dzialas, G. Bischof, K. Möllenhoff, A. Drzezga, T. van Eimeren (Cologne, Germany)

Dopamine transporter imaging to predict the risk of aspiration in patients with Parkinson’s disease

J. Tanimura, T. Yamamoto, Y. Shigemoto, N. Sato, Y. Takahashi (Kodaira, Tokyo, Japan)

Dopaminergic denervation and focal motor progression in early Parkinson’s Disease: A 5-year longitudinal study

MA. Ruiz Yanzi, M. Matarazzo, JA. Pineda-Pardo, T. Jiménez-Castellanos, MHG. Monje, A. Sánchez-Ferro, R. Martínez-Fernández, C. Gasca-Salas, JA. Obeso (Madrid, Spain)

Early changes in the locus coeruleus in mild cognitive impairment with Lewy bodies

I. Rektorova, Z. Zeleznikova, L. Brabenec, K. Mitterova, L. Novakova (Brno, Czech Republic)

Early GBA-Related Parkinson’s Disease has a Distinct Clinical Phenotype and Cholinergic Innervation

S. Slingerland, S. Zee, G. Carli, A. Slomp, E. D'Angremont, J. Boertien, T. Laar (Groningen, Netherlands)

Effects of striatal dopamine depletion and altered brain metabolism on Parkinson’s disease

HS. Yoo, PH. Lee, CH. Lyoo (Seoul, Republic of Korea)

Enlarged Perivascular Spaces in the Temporal Lobe as a Predictor for Incident Dementia in Parkinson’s Disease

HK. Na, Y. Sun, JH. Lee, CW. Park, YH. Sohn, CH. Lyoo, PH. Lee (Seoul, Republic of Korea)

Evaluating the association between cognitive impairment and striatal VMAT2 binding using [18F]AV-133 PET in Parkinson’s disease

K. Hwang, J. Langley (Long Beach, USA)

Evaluation of Glymphatic System Function in Parkinson’s disease patients using Diffusion MRI

M. Seki, R. Ueda, R. Okochi, Y. Sakai, T. Nukariya, S. Okusa, T. Tezuka, Y. Nihei, J. Nakahara (Tokyo, Japan)

Examination of how DaTscan Impacts Diagnosis in Parkinsonian Patients with and without Dopamine Receptor Blocking Agent Exposure

R. Lopez-Castellanos, S. Factor, R. Blakes (Atlanta, USA)

First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease

C. Laurencin, S. Lancelot, S. Brosse, J. Redouté, I. Mérida, D. Le Bars, N. Costes, S. Thobois, P. Boulinguez, B. Ballanger (lyon, France)

From Images to Insights: Subtyping Parkinson’s Disease Using Unsupervised Learning on MRI Data

D. Teixeira-Dos-Santos, A. De-Oliveira-Franco, A. Bieger, C. Mattjie, F. Suzuki, G. Magalhães Pereira, J. Rossi Catao, L. Angi Souza, L. Silveira Kupssinskü, L. Vinícius Moura, MA. Machado Schlindwein, R. Ravazio, S. Duarte Pinto, T. Hugentobler Schlickmann, E. R. Zimmer, MA. de Bastiani, R. C. Barros, AF. Schumacher Schuh (Porto Alegre, Brazil)

Frontal Lobe Cortical Thickness and Volumetric Analysis in Parkinson’s Disease Based on Impulse Control Disorder

R. Tripathi, D. Scarisbrick, S. Nkomboni, F. Isbaine, S. Miocinovic, D. Cobia, M. Haut (Atlanta, USA)

Functional Connectivity Changes Associated with Interlimb Coordination Force Deficits in Parkinson’s Disease

A. Bower, J. Chung, R. Burciu (Newark, USA)

Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study

B. Samanci, A. Bayram, S. Tan, M. Wanders, M. Kuijf, Y. Temel (Maastricht, Netherlands)

Hemiparkinsonism Induction with 6-OHDA in Primates Does Not Induce SN Hyperechogenicity.

L. Krejcova, W. Quaresma, L. Pedrosa, L. Leal, J. Muniz, B. Gomes (Belem, Brazil)

Hippocampal volume in Parkinson’s Disease in south India

R. Kandadai, T. Syed, A. Arora, T. Sd, S. Kola, S. Yaranagula, V. Prasad, R. Alugolu, S. Turaga, R. Borgohain (Hyderabad, India)

Identification of Brain Atrophy Subtypes in Prodromal and Overt Synucleinopathies: A Multicenter Study

S. Joza, A. Delva, C. Tremblay, A. Vo, J-F. Gagnon, R. Postuma, P. Dusek, M. Hu, J. Klein, J-P. Taylor, J. O'Brien, M. Firbank, A. Thomas, P. Donaghy, S. Lehericy, I. Arnulf, M. Vidailhet, J-C. Corvol, M. Sommerauer, S. Röttgen, S. Lewis, E. Matar, K. Ehgoetz Martens, L. Churchill, R. Camicioli, H. Chertkow, P. Borghammer, K. Knudsen, A. Hansen, D. Arnaldi, B. Orso, P. Matiioli, A. Dagher, S. Rahayel (Montreal, Canada)

Impact of Altered Cerebrovascular Reactivity on Midbrain Degeneration, Perfusion and White Matter

N. Hoffman, S. Nitschke, K. Julio, N. Shaff, A. Dodd, G. Suarez Cedeno, A. Deligtisch, D. Sugar, E. Erhardt, H. Lin, A. Vakhtin, H. Van-Der-Horn, S. Pirio Richardson, A. Mayer, S. Ryman (Albuquerque, USA)

Improved Quantification of DAT-SPECT significantly increases its Performance as an Imaging Biomarker in Parkinson’s Disease

R. Gunn, Z. Fan, D. Russell, J. Eberling, K. Marek, J. Seibyl, FOR. Ppmi (London, United Kingdom)

Increased Brain Free Water is Associated with Regional Gene Expression in Parkinson’s Disease

D. Zhang, J. Yao, H. He, T. Wu (Beijing, China)

Inflammation Biomarkers and Free Water Fraction in the Cholinergic Forebrain System in Idiopathic Parkinson’s Disease

S. Crowley, P. Kanel, S. Roytman, B. Hampstead, N. Bohnen (Charelston, USA)

Investigating the Use of 18F-DOPA PET/CT to Improve Diagnosis and Clinical Management of Parkinson’s Disease in South Australian Movement Disorder Clinics.

D. Sharma, M. Nottage, W. Vallat, R. Wilcox, M. Tan, N. Liam, A. Dwyer (Adelaide, Australia)

Longitudinal change in brain function and structure related to plasma neurofilament light protein in early-stage Parkinson’s disease

Y. Xiao, SC. Wang, YB. Hou, HF. Shang (Chengdu, China)

Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder

L. Churchill, YC. Chen, J. Anderson, A. Ignatavicius, SJG. Lewis, E. Elie (Camperdown, Australia)

Mapping Cholinergic Signaling in Parkinson Disease Using [18F]VAT

J. O'Donnell, M. Campbell, S. Norris, B. Maiti, A. Soda, S. Moerlein, Z. Tu, J. Perlmutter (St. Louis, USA)

Mapping the distribution of neurotransmitters to resting-state functional connectivity in patients with Parkinson’s disease

W. Li, N. Lao-Kaim, R. Li, A. Martín-Bastida, A. Roussakis, G. Searle, N. Valle-Guzman, V. Dayal, D. Athauda, Z. Kefalopoulou, P. Mahlknecht, A. Church, K. Peall, H. Widner, G. Paul, T. Foltynie, R. Barker, P. Piccini (London, United Kingdom)

Metabolic characteristics of brain network in patients with Parkinson’s disease after Deep brain stimulation

WEI. Lin, LJJ. Jin, KLY. Yang, HYW. Wang (WUXI CITY, China)

MIBG Uptake in the Major Salivary Glands in Patients with Parkinson’s Disease and Dementia with Lewy Bodies

J. Ebina, S. Mizumura, H. Morioka, M. Shibukawa, J. Nagasawa, M. Yanagihashi, T. Hirayama, N. Ishii, Y. Kobayashi, A. Inaba, S. Orimo, O. Kano (Tokyo, Japan)

Microstructural Changes in the Inferior Tuberal Hypothalamus Correlate with Daytime Sleepiness in Lewy Body Disease

J. Cohen, H. Radhakrishnan, C. Olm, S. Das, P. Cook, D. Wolk, D. Weintraub, D. Irwin, C. Mcmillan (Philadelphia, USA)

Mitochondrial Complex I Brain Imaging in Parkinson’s Disease and Lewy Body Dementia

S. Berman, J. Stehouwer, C. Mathis, W. Klunk, H. Tsukada, S. Royse, A. Reese, T. Overbey, J. Greenamyre, G. Sjobeck, D. Tudorascu, B. Lopresti (Pittsburgh, USA)

Morphology and Functional Connectivity of the Basolateral Amygdala and Rapid Eye Movement Sleep Behavior Disorder

Z. Song, Z. Wang, B. Zhang, J. Pu (Hangzhou, China)

Motion-robust high-resolution imaging of nigrosome-1 in Parkinson’s disease

M. Skorpil, O. Norbeck, P. Svenningsson, S. Skare, A. van Niekerk (Stockholm, Sweden)

MRI Predictive Marker of the Vestibular Galvanic Stimulation Effectiveness in the Postural Instability Treatment in Parkinson’s Disease.

O. Alenikova, A. Chumak A, G. Zobnina, D. Antonenka (Minsk, Belarus)

MRI Visible Perivascular Spaces are Associated with Disease Duration and Severity in Parkinson’s Disease

D. Hemachandra, K. Younes, E. Peterson, J. Winer, Y. Cobbigo, H. Rosen, C. Young, T. Schulte, K. Poston, E. Müller-Oehring (Palo Alto, USA)

Naturalistic walking in Parkinson’s disease: Prefrontal cortex activity measured with functional near-infrared spectroscopy (fNIRS)

R. Kaplan, N. Mukadam, C. Aul, M. Rowe, N. Eklund, T. Nordahl, M. Yücel, T. Ellis, A. Cronin-Golomb (Boston, USA)

Neural Correlates of Dual Task Touchscreen Performance in Parkinson’s Disease

J. de Vleeschhauwer, N. D'Cruz, I. Orlando, J. Tan, E. Nackaerts, W. Vandenberghe, S. Lewis, M. Shine, A. Nieuwboer (Leuven, Belgium)

Neurovascular Involvement in Parkinson’s Disease Cognitive Impairment: A 4D Flow Study

A. Deane, D. Myall, A. Pilbrow, R. Shoorangiz, A. Sharifzadeh-Kermani, T. Anderson, J. Dalrymple-Alford, C. Morgan, T. Melzer (Christchurch, New Zealand)

Parkinson’s Disease-Related Pattern in isolated REM Sleep Behavior Disorder as a prodromal progression marker

G. Carli, S. Meles, A. Dortmond, A. Janzen, E. Sittig, E. de Meyer, K. Leenders, W. Oertel (Groningen, Netherlands)

Predicting Freezing of Gait (FoG) in Parkinson’s Disease from Conventional T1-Weighted MRI

G. Rathi, A. Gardner, Z. Mari, V. Mishra (Birmingham, USA)

Quantification of Neuroinflammation and White Matter Injury in Parkinson Disease Using Diffusion Basis Spectrum Imaging

R. White Iii, J. Rutlin, B. Maiti, M. Campbell, J. Shimony, J. Perlmutter (Saint Louis, USA)

Reduced parietal and sensorimotor cortex recruitment during complex gait in Parkinson’s disease patients with freezing of gait

N. D'Cruz, M. Goris, C. Mccrum, A. Nieuwboer, M. Gilat (Leuven, Belgium)

Refining and Understanding Causal Relationships between Brain Imaging-Derived Phenotypes and Parkinson’s Disease: a Bidirectional Mendelian Randomization Study and Clinical Validation

M. Niu, Y. Zhang (Shanghai, China)

Regional Brain Volume Differences Across PD Clinical Subtypes

A. Eid, S. Grossen, A. Tanenbaum, J. Hood, H. Hwang, T. Cash, C. Lessov-Schlaggar, P. Kotzbauer, J. Perlmutter, M. Campbell (SAINT LOUIS, USA)

Resting-State Network Alterations in Patients with Isolated REM Sleep Behavior Disorder and their Association with Clinical Symptoms

I. Roura, J. Pardo, J. Oltra, A. Campabadal, Y. Compta, N. Bargallo, M. Serradell, C. Junqué, A. Iranzo, B. Segura (Barcelona, Spain)

Serotonergic dysfunction and impulse control disorders in Parkinson’s disease: a double-tracer PET study

S. Prange, E. Metereau, H. Klinger, M. Hudlestone, N. Costes, S. Lancelot, S. Thobois (Bron, France)

Severity of Motor Symptoms Correlates with Asymmetric Changes in Globus Pallidus Internus and Caudate Nuclei in Parkinson’s Disease

J. Martinez-Lemus, E. Tharp, T. Ellmore, C. Adams, R. Abuamouneh, E. Rodarte, M. Schiess (Houston, USA)

Sex Cerebral Vasoreactivity Differences in Parkinson’s Disease: Uncovering the Tip of the Iceberg

M. Cansino Torres, D. Ortiz Zacarias, A. Rodríguez Martínez, J. Trejo Ayala, S. Castillo Torres, F. Góngora Rivera, B. Chávez Luévanos, I. Estrada Bellman (Monterrey, Mexico)

Sex-Related Differences of Resting-State Brain Activity in Parkinson’s Disease

R. Li, W. Li, Y. Liu (Beijing, China)

STN-DBS Frequency Effects in Parkinson’s: An fMRI Study

A. Vijayakumari, C. Piccinin, J. Alberts, P. Bhattacharya, M. Lowe, B. Walter (Cleveland, USA)

Structural magnetic resonance imaging patterns reflect α-synuclein propagation in a model of Parkinson’s Disease

N. Betrouni, C. Katrib, K. Timmermann, D. Devos, C. Laloux (Lille, France)

Synaptic Density Loss in Parkinson’s Disease Independent of Age: Preliminary Findings using [18F]SynVesT-1 PET Tracer

S. Martin, C. Uribe, K. Desmond, N. Vasdev, A. Strafella (Toronto, Canada)

The 2-Minute Walking Test Predicts Aerobic Fitness, Motor Function, and Brain Health in Parkinson’s Disease

E. Uc, V. Magnotta, E. Axelson, J. Dawson, M. Mani, A. Comellas, J. Kline, N. Narayanan, D. Mcgehee, S. Anderson, C. Weber, W. Darling (Iowa City, USA)