Utility of Serum α-synuclein Seed Amplification Assay as a Parkinson’s Disease Biomarker
Objective: To determine the sensitivity and specificity of serum α-synuclein seed amplification assay (SAA) for Parkinson’s disease (PD) diagnosis in the Systemic Synuclein Sampling Study…Movement Disorders in the Emergency:New Insights
Objective: The study objective was to assess the clinico-epidemiological aspects of patients attending the Emergency with movement disorder as the primary symptom. Background: Available literature…Wilson’s Disease About A Complex Case
Objective: We report the case of a patient who experienced diagnostic wavering. Background: Wilson disease is a rare disease. Cases in Africa is even rarer.…A Phase 2 Study of ATH434 a Novel Inhibitor of α-Synuclein Aggregation for the Treatment of Multiple System Atrophy
Objective: Describe baseline fluid and neuroimaging biomarker data of an early MSA study population Background: MSA is a rapidly progressive neurodegenerative disorder characterized by aggregated…Seed Amplification Assay for the differentiation of αSyn seed subtypes
Objective: To identify soluble αSyn-seed types present in brain homogenate (BH) and CSF using αSyn seed amplification assay (synSAA) Background: Lewy bodies and neurites are…Increasing diagnostic accuracy of Multiple System Atrophy – A Videolibrary on clinical and imaging features
Objective: To provide short, high-quality videos and MRI images presenting typical MSA features to supplement new MDS-MSA criteria1. Background: The MDS criteria for the diagnosis…Peripheral immune profile and neutrophil-to-lymphocyte ratio in Progressive Supranuclear Palsy
Objective: This study aimed to evaluate the peripheral immune profile in patients with Progressive Supranuclear Palsy (PSP) compared with patients with Parkinson’s disease (PD) and…The Clinical Landscape of Progressive Supranuclear Palsy in an Underserved Community from Southwestern Colombia
Objective: To elucidate the clinical presentation of Progressive Supranuclear Palsy (PSP) in a cohort residing in underserved communities in Buenaventura, Colombia—the country's primary maritime port…Impact of Prior Head Trauma on Parkinson’s Disease Experience
Objective: We aim to characterize the impact of prior head trauma on Parkinson’s disease (PD) related outcomes. Background: Previous head trauma is correlated with detrimental…Preventing Treatment Disruptions: The Crucial Role of Outpatient Nurses and Multidisciplinary Collaboration in Managing Skin Complications during Foslevodopa/Foscarbidopa Therapy
Objective: The objective of this research was to explore the pivotal role of outpatient nurses in mitigating skin complications and facilitating uninterrupted treatment for Parkinson's…
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