Age and Parkinson’s disease: clinical and biomarkers profiling of younger and older patients
Objective: Given the well-known clinical differences and natural history of Parkinson's disease (PD) according ot patients age, wthis study aims at exploring the different pathophysiological…Cortical and Subcortical Brain Volume Changes in Idiopathic REM Sleep Disorder Subjects at Risk for Parkinson’s Disease
Objective: To quantify cortical and subcortical brain volumes using structural MRI analysis in idiopathic REM sleep behavior disorder (iRBD) subjects at risk for Parkinson`s disease…Frontal atrophy in progressive supranuclear palsy[PSP] -an universal feature along with midbrain atrophy?
Objective: To see if frontal atrophy is a frequent radiologic feature of PSP on MRI imaging . Background: Progressive supranuclear palsy[PSP] is a taupathy that…Identification of Brain Atrophy Subtypes in Prodromal and Overt Synucleinopathies: A Multicenter Study
Objective: To identify unique subtypes of synucleinopathy with distinct spatiotemporal patterns and trajectories of brain atrophy and disease burden. Background: The synucleinopathies manifest as a…Clinical and Brain Morphological Characteristics of Early LRRK2-associated Parkinson Disease
Objective: To investigate the impact of LRRK2 mutation in Parkinson disease (PD) and to explore the preclinical markers of LRRK2 mutation carriers who will develop…Associations between Choroid Plexus and tau in Parkinson’s Disease
Objective: To investigate the associations between the choroid plexus (ChP) and protein indicators of Parkinson’s Disease (PD). Background: The ChP is the primary organ that…Data-driven image-based subtyping and staging of neurodegeneration in Parkinson’s disease
Objective: We aimed to conduct image-based, data-driven classification of Parkinson’s disease (PD) progression using event-based modeling (EBM) and derive neuropathological insights from the results. Background:…Regional Brain Volume Differences Across PD Clinical Subtypes
Objective: To investigate brain morphometric differences across Parkinson disease (PD) clinical subtypes. Background: We developed a PD subtype classification with three subtypes that includes motor…The Feasibility of ICA in Parkinson’s Disease fMRI
Objective: To report the feasibility of ICA on the BOLD signals of a Parkinson’s Disease patient. Background: ICA is a mathematical method to decompose multivariate…Deep Brain Stimulation of bilateral ventral intermediate nucleus in a patient with spinocerebellar ataxia type 12
Objective: To treat the medication-resistant tremor of SCA12 by Deep brain stimulation (DBS) Background: Action tremor might be the most prominent feature of SCA12 patient…
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