Path To Prevention (P2P) Therapeutics Platform Trial in Stage 2B Neuronal Alpha-Synuclein Disease: Study Update
Objective: To describe the study design and timeline of the first interventional study in Neuronal α-Synuclein Disease (NSD). Background: P2P is a platform, Phase 2…New α-Synuclein Strain Biomarker in Parkinson’s Disease and Related Dementia
Objective: Biomarker development for Parkinson’s disease and related dementia. Background: α-Synuclein (α-syn) strains can serve as discriminators of Parkinson's disease (PD) from other α-synucleinopathies. However,…Association of β-Amyloid Load on PET with Cognitive Profiles Across the Lewy Body Diseases Continuum
Objective: To investigate the association between Aβ accumulation and clinical characteristics across the Lewy body disease (LBD) spectrum, with a specific focus on global and…Trihexyphenidyl Use in a Parkinsonian Phenotype of Gerstman-Sträussler-Scheinker Syndrome
Objective: To highlight clinical improvement in a patient with a parkinsonian presentation of Gerstmann-Sträussler-Scheinker (GSS) syndrome who was treated with trihexyphenidyl. Background: GSS is a…Behind the wheel with Parkinson’s-Older patients’ review
Objective: To review characteristics of older Parkinson’s patients undergoing driving assessments presenting to Movements disorder’s clinic at Royal Berkshire Hospital, Reading,UK. Background: Parkinson’s leads to…Body Mass Index as a Possible Poor Prognostic Factor in Motor and Postural Condition Through the Evaluation of MDS-UPDRS 3.3 – 3.18 in Patients with Parkinson’s.
Objective: To determine the degree of motor and postural impairment of patients with Parkinson's Disease at the time of their first consultation according to the…Disease-related comprehensive motor pattern derived from 2D single RGB video as a biomarker for early and prodromal Parkinson disease
Objective: This study aims to develop a disease-related motor pattern from a single 2D RGB video as a biomarker for early diagnosis and monitoring of…Dopaminergic alterations in patients with Alzheimer’s disease
Objective: The objective of this study was to conduct a meta-analysis to determine the pooled mean difference (MD) in dopaminergic measures between Alzheimer’s disease and…SelfCog®: A 15-min Digitized Cognitive Battery To Measure Cognitive Deficit In Parkinson Disease (PD) Patients
Objective: Use a news automated, motor-controlled cognitive battery, the SelfCog®, to compare cognitive deficits in PD patients. Background: Mild cognitive impairment (MCI) is a major…To develop and study the efficacy of Telephonic Psychotherapy on the Global Neuropsychological functioning of PD Patients: An RCT
Objective: A single blinded RCT was conducted to develop and test the efficacy of a telephonic psychotherapy on PD Patients. PD patients bound by movement…
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