Quality of life assessment in patients with Parkinson’s disease
Objective: The objective of the study was to assess the quality of life in patients with Parkinson's disease (PD) and to establish statistical correlations with…Patient and Caregiver Experiences with Huntington Disease: Emotions, Challenges, and Unmet Needs in the Patient Journey
Objective: To describe patients' emotional journey from symptom onset and diagnosis to current state and to identify challenges and unmet needs in Huntington disease (HD).…Ecopipam does not adversely affect Metabolic Parameters in Pediatric Subjects with Tourette Syndrome: Results from a Phase 2b with 12-month Open Label Extension Study
Objective: Determine if ecopipam is associated with the emergence of clinical features suggestive of metabolic syndrome in pediatric subjects with Tourette Syndrome (TS) Background: Dopamine-2…Long-term evaluation of advanced Parkinson’s disease burden and clinical outcomes: results from the PROSPECT observational study
Objective: Evaluate long-term clinical outcomes and disease burden in people with advanced Parkinson's disease (PwP) with motor fluctuations not optimized by their current medications. Background:…Characterization of Infusion Site Reactions With 24-hour Subcutaneous Infusion of ND0612
Objective: To characterize infusion site reactions (ISRs) reported as adverse events (AEs) in clinical studies of ND0612. Background: ND0612 is an investigational, subcutaneous infusion of…Effect of Opicapone and Levodopa on the Different Daily OFF Patterns in Patients with Parkinson’s Disease and Early Motor Fluctuations: Findings from the Korean ADOPTION Study
Objective: To evaluate the effect of opicapone (OPC) 50 mg versus an additional 100 mg levodopa (L-DOPA) dose on the different daily OFF patterns in…Assessing a Video Based Approach at Measuring Parkinson’s Disease Severity – A Validation Study
Objective: To validate the Parkinson’s remote interactive monitoring system’s assessment of Parkinson’s disease compared to a clinical assessment completed by a movement disorder specialist. Background:…Remote recruitment of hyposmic participants identifies biomarkers related to neuronal alpha-synuclein disease
Objective: To evaluate the proportion of people with dopaminergic deficit and positive alpha-synuclein seed amplification assay (aSyn SAA) among a remotely identified group of hyposmic…Safety and tolerability of opicapone in Parkinson’s Disease: from early-stage (EPSILON study) to late-stage (BIPARK studies)
Objective: To compare the safety and tolerability of once-daily opicapone (OPC) 50mg as add-on to stable levodopa/dopa decarboxylase inhibitor (L-DOPA/DDCI) therapy in patients from early…Remotely-deployed gamification intervention to increase physical activity in Parkinson’s Disease
Objective: To describe a remote, behavioral intervention designed to increase daily steps in Veterans with PD and report interim results from an ongoing clinical trial…
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