Frequency of Variants of Uncertain Significance in a Cohort of Early-onset Parkinson’s Disease Patients
Objective: Aim of the study is to report the frequency of variants of uncertain significance (VUS) in a cohort of patients with early-onset Parkinson’s disease…Laboratory changes of the liver function in the patients with Wilson’s disease
Objective: Wilson's disease (WD) is a chronic progressive neurodegenerative disease with a genetically determined disorder of copper metabolism due to mutations in the ATP7B gene,…Movement Disorder Presentations in Leukoenephalopathy with Calcifications and Cysts
Objective: The aim of this study is to describe the movement disorder phenotypes within a cohort of individuals with Leukoencephalopthy with Calcifications and Cysts. Background:…Tetradystonics patients may be misdiagnosed?
Objective: Present a case of movement disorder that genetic panel hasn’t tracked in the screening, and it’s stabilization with L-carnitine. Background: isobutyryl-CoA dehydrogenase deficiency is…Basal ganglia theta oscillation as a predictor of levodopa-induced dyskinesias
Objective: To investigate the temporal and spatial relationship between local field potential (LFP) changes and dyskinesia development. Background: Levodopa-induced dyskinesias (LID) are an important burden…Linear Mixed-Effect Modelling of Antisaccades in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: This study aims to investigate variations in antisaccade parameters (latency, damping ratio, peak velocity, and amplitude) among different stages of Parkinson's Disease (PD), Progressive…The Inhibition of Mitochondrial NLRP3 Inflammasome Decreases Dopaminergic Cell Death in a 6-OHDA Mouse Model of Parkinson’s Disease.
Objective: To evaluate the possible neuroprotective effects of mitochondrial NLRP3 inflammasome inhibition in a 6-hydroxydopamine mouse model of Parkinson's Disease. Background: Overactivation of brain immune…Do Proton Pump Inhibitors Increase the Risk of Parkinson’s Disease? A systematic review and meta-analysis
Objective: To provide an updated meta-analysis of the observational studies examining the association between proton pump use and Parkinson’s disease. Background: The exact cause of…Study of Cytokine profile in a Tunisian Parkinson’s Disease cohort
Objective: We aim to study the relationship between clinical features in patients with Parkinson’s disease (PD) and their IL-6 and IL-1β serum levels. Background: According…Muscle co-contraction in people with Parkinson’s disease suffering from freezing of gait
Objective: 1) to test the feasibility of using novel, disposable EMG electrodes to study co-contraction (CC) and 2), to test if muscle CC is higher…
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