The functional and lipidome signature of GBA1 mutant dopaminergic neurons
Objective: The work presented here aims to link the lipidome changes leading to functional defects, and eventual cell death, in GBA1 mutant dopaminergic neurons derived…Diffusion MRI and Machine Learning Distinguish Alzheimer’s Disease and Dementia with Lewy Bodies
Objective: This study reports recent updates in the development of a support vector machine learning model to discriminate between dementia variants (i.e., Alzheimer’s disease (AD)…Increased Brain-Age Gap Estimate (BrainAGE) in Neurological Wilson Disease
Objective: To assess grey matter (GM) volume derived brain-aging in Wilson Disease (WD) using a previously proposed machine learning (ML) algorithm. Background: GM atrophy is…Association of Striatal Dopaminergic Depletion, Cerebral Perfusion, and Cognitive Outcome in Brain-first and Body-first Parkinson’s Disease
Objective: This study investigated whether brain-first and body-first Parkinson’s disease (PD) showed different pattern of subregional striatal dopamine loss and cerebral perfusion using dual-phase 18F-FP-CIT…MIBG Uptake in the Major Salivary Glands in Patients with Parkinson’s Disease and Dementia with Lewy Bodies
Objective: The aim of the study was to compare the metaiodobenzylguanidine (MIBG) uptake in the major salivary glands (MSG) in patients with Parkinson’s disease (PD)…Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease
Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…Parkinson’s Disease-Related Pattern in isolated REM Sleep Behavior Disorder as a prodromal progression marker
Objective: To investigate expression of the PD-related pattern in 18F-FDG PET scans of iRBD patients longitudinally. Background: The Parkinson’s disease-related pattern (PDRP) might serve as…Dopaminergic denervation and focal motor progression in early Parkinson’s Disease: A 5-year longitudinal study
Objective: To evaluate the progression of posterior putamen dopaminergic denervation in relation to motor progression in the less affected and more affected side of the…Frontal Lobe Cortical Thickness and Volumetric Analysis in Parkinson’s Disease Based on Impulse Control Disorder
Objective: Characterize differences in frontal cortical thickness and volumes in Parkinson’s disease based on impulse control disorder. Background: Impulse control disorder (ICD) is a debilitating…Deep Brain Stimulation (DBS) Improves Parkinsonism Caused by Osmotic Demyelination Syndrome (ODS)
Objective: We present a report on a successful case wherein Deep Brain Stimulation (DBS) was employed to alleviate Parkinsonism in a patient suffering from Osmotic…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.