MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2024 International Congress

    Gender Disparities in Quality of Life Domains Among Hispanic Individuals with Parkinson’s Disease: A Comparative Analysis

    D. Bustamante-Mieles, C. Rodriguez-Alarcon, D. Piana-Castillo, G. Faggioni-Sanchez, C. Cevallos-Velasco, M. Barreiro-Guillén, R. Santibanez-Vasquez (Guayaquil, Ecuador)

    Objective: This study aims to determine gender differences in the quality of life of Parkinson's disease (PD) among Hispanic individuals. Background: PD profoundly affects various…
  • 2024 International Congress

    Deep Brain Stimulation From the Perspective of Relatives and Caregivers: A Qualitative Analysis and Caregiver Burden

    TUC. Saltoglu, YSK. Sücüllü Karadağ (İNCEK, Turkey)

    Objective: One of the most important conditions for success in Deep brain stimulation (DBS), which has been proven effective for more than thirty years and…
  • 2024 International Congress

    Participant-reported personal utility of genetic testing for Parkinson’s disease and interest in clinical trial participation

    J. Verbrugge, H. Oas, L. Cook, T. Schwantes-An, L. Walsh, T. Foroud, K. Marder, I. Mata, N. Mencacci, T. Simuni, M. Nance, M. Schwarzschild, A. Wills, S. Lawrence, A. Hall, A. Naito, J. Beck, R. Alcalay (Indianapolis, USA)

    Objective: To investigate whether participants in the PD GENEration study (NCT04994015) perceived personal benefit from receiving genetic testing for Parkinson’s disease (PD), whether being tested…
  • 2024 International Congress

    ORION: A Global Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of AMX0035 in Progressive Supranuclear Palsy (A35-009)

    A-M. Wills, G. Höglinger, L. Mehta, M. Leinders, Y. Wu, J. Timmons, A. Hayden, I. Aiba, A. Antonini, A. Boxer, Y. Compta, J-C. Corvol, A. Lang, H. Morris, P. Svenningsson, H. [email protected], L. Golbe (Boston, USA)

    Objective: Here we describe ORION, a phase 3 trial assessing efficacy and safety of AMX0035 in progressive supranuclear palsy (PSP). Background: PSP is a rare,…
  • 2024 International Congress

    Sleep disorders in Parkinson’s disease

    M. Mirqosimova (Dushanbe, Tajikistan)

    Objective: to specify the clinical features of sleep disorders in patients with PD and their impact on quality of life indicators; assessment of the relationship…
  • 2024 International Congress

    Assembling a Cohort of Hyposmic Participants for Therapeutic Studies Aimed at Parkinson’s Disease (PD) Prevention

    B. Mcmahon, L. Lemon, R. Dobkin, E. Brown, J. Dimos, M. Kuhl, L. Heathers (Baltimore, USA)

    Objective: The goal of this project was to amass a cohort of individuals with hyposmia to later invite them to participate in clinical trials for…
  • 2024 International Congress

    Dopaminergic Adverse Events With 24-hour Subcutaneous Infusion of ND0612

    S. Isaacson, O. Rascol, H. Sarva, R. Hauser, F. Stocchi, N. Lopes, L. Salin, J. Pereira, N. Giladi (Boca Raton, USA)

    Objective: Characterize dopaminergic treatment-emergent adverse events (TEAEs) reported with 24h ND0612 treatment in clinical studies. Background: Dopaminergic adverse events are commonly reported across the spectrum…
  • 2024 International Congress

    NouvNeu001, A Phase 1 Stage Chemically Induced Human Dopaminergic Progenitor Cell Therapy for the Treatment of Mid- to Late-stage Parkinson’s Disease

    M. Cai, J. Wei, X. Ren, R. Yan, H. Chen, N. Xiong (Wuhan, China)

    Objective: To access the efficacy and safety of NouvNeu001 in models of Parkinson’s Disease (PD) and a Phase 1 clinical trial (NCT#06167681). Background: Parkinson's disease…
  • 2024 International Congress

    ENLITE PD – A Dose Selection Trial of Light Therapy for Impaired Sleep in Parkinson’s Disease

    A. Videnovic, E. Macklin, C. Coffey, M. Cudkowicz, HJ. Cho, J. Ohayon, A. Amara, K. Marder, P. Zee, C. Desir, H. Ernst, E. Steinhart, M. Costigan, A. Gudjonsdottir, D. Ecklund, M. Chase, S. Criswel, D. Charles, J. Coleman, A. Espay, A. Hung, S. Kadimi, A. Killoran, L. Luo, R. Malkani, J. Margolesky, J. Marsella, C. Maurer, D. Mihaila, P. Moretti, A. Park, P. Phielipp, H. Sarva, B. Shah, H. Shill, A. Siderowf, V. Suski, J. Tate, W. Tse, K. Wyant, L. Zhang, E. Klerman (Boston, USA)

    Objective: To determine if either once or twice-daily bright white light therapy (BWLT) improves sleep sufficiently relative to two control LT conditions to warrant proceeding…
  • 2024 International Congress

    Lithium Therapy Associated with Reductions in Serum Neurofilament Light Chain (NfL) in Parkinson’s Disease.

    T. Guttuso, JR., R. Shepherd (Williamsville, USA)

    Objective: To assess the effects of lithium aspartate and lithium carbonate therapy for 24 weeks on serum NfL in Parkinson’s disease (PD). Background: Lithium has…
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