IGF2 Induce Neuroprotection in PD Preclinical Models by Modulation of Immune Response.
Objective: We propose to determine a therapeutic strategy based on adoptive transfer of macrophages reprogrammed for recombinant IGF2 (rIGF2) treatment in PD preclinical model. Background:…Essential Tremor: The Relationship Between Hand Dominance and Tremor Severity by MVPA
Objective: The objective of this study was to analyze task-based functional Magnetic Resonance Imaging (task-fMRI) to investigate neural activity patterns in individuals diagnosed with Essential…A group of patients with multiple system atrophy (MSA) exhibit cardiac sympathetic dysfunction to the same extent as Parkinson’s disease (PD).
Objective: Although there are cases of multiple system atrophy (MSA) with decreased MIBG, there has not been sufficient investigation into the proportion. Thus, we retrospectively…Analysis of structural connectivity in relation to change in dopaminergic medication after 6 months of STN-DBS in Parkinson´s disease – a pilot study
Objective: To describe the relationship between structural connectivity and it´s effect on change in levodopa equivalent daily dose (LEDD) in patients 6 months after subthalamic…Abnormal basal ganglia-related functional gradient in Parkinson’s disease
Objective: The aim of this research was to investigate the basal ganglia (BG)-related functional gradient alterations and the association between these brain dysfunctions and clinical…Impact of Altered Cerebrovascular Reactivity on Midbrain Degeneration, Perfusion and White Matter
Objective: To evaluate whether altered cerebrovascular reactivity contributes to midbrain degeneration, perfusion abnormalities, or white matter disease in patients with Parkinson’s disease (PD). Background: Cerebrovascular…Improved Quantification of DAT-SPECT significantly increases its Performance as an Imaging Biomarker in Parkinson’s Disease
Objective: To investigate potential improvements in signal-to-noise (SNR) derived from advanced image analysis of longitudinal DAT-SPECT data. Background: [123I]Ioflupane SPECT (DAT-SPECT) has been widely used…Transcranial Sonography of the Substantia Nigra and Vagus Nerve Ultrasonography as Complementary Diagnosis for Parkinson’s Disease.
Objective: We aim to investigate the relationship between sonographic abnormalities of the substantia nigra, vagus nerve cross-sectional area and clinical features of PD in different…Early changes in the locus coeruleus in mild cognitive impairment with Lewy bodies
Objective: To evaluate NMS signal changes in the locus coeruleus (LC) in mild cognitive impairment with Lewy bodies (MCI-LB) as compared to healthy controls (HC)…Safety of staged bilateral MR-guided focused ultrasound thalamotomy for essential tremor
Objective: To evaluate the efficacy and safety of staged bilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in patients with medication-refractory bilateral essential tremor (ET). Herein,…
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