Opicapone real-world experience in early motor fluctuations: 3-months analysis of the REONPARK study.
Objective: The REONPARK study aims to evaluate COMT inhibitor (iCOMT) effectiveness and tolerability in alleviating motor complications associated with L-dopa treatment in Parkinson’s Disease patients…One dose fits all? An analysis of the levodopa equivalent dose over time in Parkinson’s disease
Objective: To ascertain and delineate the differences in Levodopa Equivalent Dose (LEDD) among Parkinson’s disease (PD) subtypes and to examine its evolution over the disease’s…The impact of long-term continuous subcutaneous apomorphine infusion on the reduction of remaining medications in levodopa equivalent dosage and on increasing plasma vitamin B12 levels in patients with advanced Parkinson’s disease
Objective: To evaluate the plasma levels of vitamin B and homocysteine among 28 advanced PD patients with motor complications before and after continued used of…Pathological Mechanisms Associated with Atrazine-Induced Parkinson’s Disease Pathogenesis in Rat Model: The Rescue Role of Myricetin
Objective: This study aimed at investigating the mechanisms involved in the pathogenesis of Parkinson’s Disease in atrazine rat model of Parkinson’s Disease and the neuroprotective…TM9SF2 Knockdown Decreases Pathological Alpha-synuclein Aggregation In Vivo
Objective: To determine whether knockdown of transmembrane 9 super family 2 (TM9SF2) decreases the formation of alpha-synuclein inclusions and toxicity to nigral neurons in the…Alpha-Synuclein and Mitochondria Quality Control in Parkinson’s Disease: A Literature Review
Objective: To provide an overview of the current knowledge on alpha-synuclein (αS) interactions with mitochondrial quality control (MQC) pathways in Parkinson’s disease (PD). Background: The…Association of Retinol Binding Protein (RBP) and the Risk of Parkinson’s disease (PD): A Narrative Literature Review
Objective: This review aimed to investigate the association between RBP levels and the risk of Parkinson’s disease Background: RBP facilitates retinol transport from the liver…Developing a Supervised Machine Learning Model for Long-Term Cognitive Status Prediction in Parkinson Disease
Objective: The study aims to develop a supervised machine learning (ML) model to predict long-term cognitive outcome in patients with Parkinson disease (PD). Background: Cognitive…Exploring Quantitative Susceptibility Mapping in Wilson’s Disease- A Prospective Cohort Study
Objective: To describe the quantitative magnetic susceptibility(QSM) in Wilson’s disease (WD) and healthy controls Background: Quantitative susceptibility mapping (QSM) is a post processing technique that…STN-DBS Frequency Effects in Parkinson’s: An fMRI Study
Objective: The study aimed to investigate the impact of deep brain stimulation (DBS) at varying frequencies on brain activation patterns during a motor (force-tracking [FT])…
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