Adult-onset Niemann-Pick C in India: phenotype and genotype
Objective: This study was aimed to describe the clinical, radiological, and molecular profile of adults affected by NPC. Background: Adult-onset Niemann-Pick C (NPC) is a…Clinical, Neurophysiological, and Biological Insights into Levodopa-Induced Dyskinesias
Objective: The aim of this study was to determine the clinical, neurophysiological and biological features of Parkinson's Disease (PD) patients with L-Dopa-induced dyskinesias (LIDs). Background:…Quantification of an Upper Limb Rigidity Network in Parkinson Disease
Objective: To explore the cortico-subcortical network related to rigidity. Background: Rigidity of the upper limb is one of the cardinal symptoms in Parkinson’s disease (PD),…Exploring the Therapeutic Potential of Microglial Modulation in Parkinson’s Disease: A Study on Structural Synaptic Plasticity
Objective: We aim to explore the role of glial cells in Parkinson's disease and assess whether modulating microgliafunction could offer therapeutic benefits. Specifically, we investigate…Eye Blink Rate and Putamen DaTScan Covariation in Parkinson’s Disease
Objective: To examine the relationship between blink rate and DaTScan in Parkinson’s disease. Background: Spontaneous eye-blink rate (BR) is blinking without external triggers. Parkinson's disease…Genetic Variants and Levodopa Response in Parkinson’s Disease: Insights from MAO-B and DAT1 Polymorphisms
Objective: This study aimed to find the association of genetic variations between Parkinson’s disease (PD) patients with and without levodopa-induced dyskinesia (LID). we intended to…Decline in functionality according to WHODAS 2.0 associated with disease progression in people with Parkinson’s disease
Objective: To investigate the decline in functionality according to WHODAS-2.0 from early to intermediate stages of PD. Background: Parkinson's disease (PD) is an incurable and…Lessons from the COVID-19 Lockdown: A Novel Mentorship Program for Young Neurosurgeons, Neurologists and Medical Students
Objective: To propose novel virtual mentorship program as a teaching tool to improve career skills among young Neurosurgeon and Ophthalmologists. Background: COVID‐19 pandemic has caused…Evaluation of Neurotransmitter and Co-transmitter Expression in the Aging Human Locus Coeruleus: Relevance to Neurodegenerative Disorders.
Objective: To analyze the age-associated changes in the neurotransmitter/co-transmitter expression and morphometric profiles of human locus coeruleus (LC) neurons using autopsied human tissues. Background: LC…The Pro-LBD Study Investigating Early Detection, Prognosis, and Biomarkers of Prodromal Lewy Body Diseases
Objective: The Pro-LBD cohort study is a prospective, long-term, clinic-biological cohort study of participants who are stratified by their risk of developing a Lewy body…
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