Pre-treatment with Methanolic Extract Mucuna pruriens Seeds Attenuates Serotonin Gene Depletion, Motor Dysfunction and Anxiogenic Responses in a Rat Model of Parkinsonism
Objective: Investigate neuroprotective and genoprotective effects of methanolic Mucuna pruriens (Mp) seed extract in a paraquat-induced Parkinsonism rat model. Background: Paraquat exposure has been linked…Nocturnal Hypertension in Parkinson’s Disease. The Flip Side of a Tainted Coin
Objective: To describe prevalence and severity of nocturnal hypertension and dipping in a cohort of patients with Parkinson’s disease undergoing 24hr blood pressure (BP) monitoring.…Carbidopa does not cause changes in QTc interval even at a supratherapeutic dose
Objective: To assess the cardiac safety of a single supratherapeutic dose of carbidopa in healthy adults. Background: Carbidopa has been approved for use in combination…Palliative Care in Advanced Parkinson’s Disease: Descriptive Analysis and Symptom Impact
Objective: These preliminary study aims to describe the primary clinical features of Parkinson's disease patients requiring palliative care, as assessed by the Edmonton Symptom Assessment…A case of malignant Deep Brain Stimulation Withdrawal Syndrome treated with Opicapone
Objective: We present a case of a patient with Parkinson's disease who developed "malignant Deep Brain Stimulation (DBS) Withdrawal Syndrome" following the removal of the…Understanding the neuroprotective mechanism of ilex Paraguariensis (Yerba mate) in a Drosophila melanogaster alpha-synuclein model of Parkinson’s disease
Objective: To investigate behavioral and cellular changes in the brain of a Drosophila melanogaster model of Parkinson’s Disease (PD) exposed to yerba mate [YM] extract.…Consistent downregulation of rarely reported antioxidant genes viz., GGL, TR, TrX, HO-1, GR, GS, in the mid brain regions among mice and Drosophila exposed to Parkinsonian toxins: Scope as early diagnostic markers
Objective: The study aimed at deciphering status of redox genes in mid-brain regions of 2 major in vivo study models: mice/Drosophila melanogaster exposed to Parkinson…Transcriptomic and Proteomic Profiling for Effective Deep Brain Stimulation in Parkinson’s Disease
Objective: To determine whether transcriptomic and proteomic changes predict better motor outcomes after deep brain stimulation (DBS) surgery in Parkinson’s disease (PD). Background: DBS is…IGF2 Induce Neuroprotection in PD Preclinical Models by Modulation of Immune Response.
Objective: We propose to determine a therapeutic strategy based on adoptive transfer of macrophages reprogrammed for recombinant IGF2 (rIGF2) treatment in PD preclinical model. Background:…Essential Tremor: The Relationship Between Hand Dominance and Tremor Severity by MVPA
Objective: The objective of this study was to analyze task-based functional Magnetic Resonance Imaging (task-fMRI) to investigate neural activity patterns in individuals diagnosed with Essential…
- « Previous Page
- 1
- …
- 105
- 106
- 107
- 108
- 109
- …
- 181
- Next Page »