Wavelet-based bracketing, time-frequency beta-burst detection: new insights in Parkinson’s disease
Objective: To identify bursts in wide frequency bands and show the relation between burst features and clinical scores. Background: Beta burst activity is a pathophysiological…The Pistol Sign
Objective: To describe a specific dystonic feature associated with corticobasal degeneration(CBD). Background: Dystonia is common in atypical parkinsonian disorders such as multiple system atrophy, progressive…Factors influencing health-related quality of life of patients with spinocerebellar ataxia
Objective: The objective was to demonstrate the progression of HRQoL over time and identify factors affecting SCA patients' HRQoL. Background: Spinocerebellar ataxias (SCA) comprise a…A case of progressive ataxia with palatal tremor (PAPT) syndrome due to idiopathic bilateral hypertrophic olivary degeneration
Objective: To describe a patient with Progressive Ataxia with Palatal Tremor (PAPT) syndrome due to Idiopathic Bilateral Hypertrophic Olivary Degeneration Background: Hypertrophic olivary degeneration (HOD)…An uncommon task specific dystonia masquerading as Myasthenia Gravis
Objective: We present a case of late onset task specific segmental (cervico-lingual) dystonia misdiagnosed as bulbar myasthenia gravis. Background: Muscle diseases have been previously reported to mimic…Correlation of clinical profile of Parkinsonism with molecular imaging
Objective: CORRELATION OF CLINICAL PROFILE OF PARKINSONISM WITH MOLECULAR IMAGING (TRODAT AND PET-CT BRAIN) Background: The current study aims to establish the role of Molecular…Regional brain volume and cognitive alterations in Huntington’s Disease Patients
Objective: To investigate i) HD patterns of cortical and subcortical atrophies ii) associations between atrophy and clinical, motor and cognitive features. Background: Huntington’s disease (HD)…A human tissue engineered nigrostriatal system as a testbed for understanding PD pathophysiology and therapeutic development
Objective: The objective of these studies is to develop a tissue engineered nigrostriatal system involving human dopaminergic and striatal cells to recapitulate many of the…RNA editing contributes to the inflammatory astrocytic response in Parkinson’s disease.
Objective: 1) Using an IPSC derived cell model to explore astrocytic responses alone and cocultured neurons to alpha-synuclein oligomer (αsynO) treatment.2) Determine the extent to…Combined GWAS of Dementia with Lewy Bodies, REM-Sleep Behavior Disorder, Parkinson’s Disease and Alzheimer’s Disease
Objective: To identify genetic variants that are either shared between or specific for Dementia with Lewy Bodies (DLB), REM Behavior Disorder (RBD), Parkinson’s disease (PD)…
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