Distinct striatal connectivity patterns in patients with Parkinson’s disease with and without urinary symptoms
Objective: To investigate the potential effect of urinary symptoms on the regional striatal functional connectivity (FC) in a cohort of drug-naïve PD patients applying a…Progressive myoclonus ataxia and resting tremor in hypoceruloplasminemia
Objective: To describe two familiar cases of hypoceruloplasminemia presenting with movement disorders Background: Aceruloplasminemia is a metabolic disorder caused by mutations in the ceruloplasmin (CP)…Patterned alternating-coloured strips for freezing of gait – Novel solution for a disabling symptom.
Objective: To evaluate a novel method of visual cueing using patterned alternating-coloured strips made of electrical tape for freezing of gait. Background: Freezing of gait…Assessing akinesia domains during multitasking in Parkinson’s disease
Objective: To explore performance differences in single- versus dual-tasking conditions between healthy controls (HC) and Parkinson's disease (PD) patients. Background: Akinesia, comprising slowness (bradykinesia), reduction…Oculomotor changes in the premotor stage of LRRK2- G2019S associated Parkinson’s disease.
Objective: To analyse oculomotor differences among idiopathic PD patients (iPD), LRRK2-G2019S PD patients (LRRK2-G2019S PD), asymptomatic carriers of LRRK2-G2019S mutation (AsG2019S), and controls, evaluated by…New wearable technology for quantification of freezing of gait in school going adolescent with pediatric movement disorders
Objective: To study quantification of freezing of gait (FOG) and falls of patients data in school going adolescent with pediatric movement disorders by wearable device…First case of sporadic ATP6AP2 Mutation reported in Asia in a Parkinson’s Disease patient
Objective: Genetic analysis of Parkinson's Disease (PD) with features of spasticity by Whole Exome Sequencing (WES) and use of its result for treatment modification to…Deep Brain Stimulation in Parkinson’s Disease Patients: A One Year Follow-up in the Understudied Geography of Brazil
Objective: This study aimed to evaluate the role of deep brain stimulation (DBS) in the improvement of health-related quality of life (HR QoL) outcomes in…Evaluation of a novel Phosphodiesterase 5 inhibitor as a potential therapeutic agent in P301S transgenic mouse model of tauopathy.
Objective: In the current study, we evaluated a newly developed compound with a 1,3,5-trisubstituted pyrazoline scaffold with an improved PDE5 inhibitory potency as a potential…Concordant RNA patterns in Parkinson’s disease brain and peripheral blood.
Objective: To investigate the molecular correlates of clinical heterogeneity in Parkinson’s disease (PD) in the striatum and peripheral blood. Background: The molecular basis for clinical…
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