Neuroprotective properties of arylpiperazine-sulphonamides in an in vitro model of Parkinson’s disease
Objective: To investigate the neuroprotective effects of novel arylpiperazine compounds as measured by viability of SH-SY5Y cells in vitro. Background: Parkinson’s disease (PD) is a…Istradefylline therapy for PD plus oromandibular dystonia
Objective: To clarify the dopaminergic system link between parkinson's disease (PD) and oromadibular dystonias (OMDy) co-occur, and the effect of istradefylline (IST) therapy. Background: OMDy are…Risk Factors for Stimulation-Induced Bradykinesia in Dystonia Patients Treated with Deep Brain Stimulation: A Retrospective Analysis.
Objective: Identification of risk factors for stimulation-induced bradykinesia in GPi-DBS Background: Deep brain stimulation (DBS) is an effective treatment for dystonia, but some patients may…Effectiveness of use of Pictographs on Levodopa packaging to ensure awareness of Levodopa/Carbidopa spacing with meals in patients of Idiopathic Parkinson’s disease.
Objective: Food interferes with gastrointestinal absorption of levodopa which requires spacing with meals. This study aimed to evaluate the effect pictographs on Levodopa packaging Fig 1 on increasing patient…Addition contact with 10 Hz stimulation in the STN may improve stimulation-induced cognitive disturbances
Objective: This case report demonstrates improvement of cognition by adding low-frequency stimulation in the ventral subthalamic nucleus (STN). Background: Deep brain stimulation (DBS) targeting the…Longitudinal association of mild behavioral impairment with cognitive decline in Parkinson’s disease
Objective: To analyze the cross-sectional and longitudinal association between mild behavioral impairment and cognitive impairment in Parkinson’s disease. Background: Cognitive impairment and neuropsychiatric symptoms (NPS)…ParkProReakt Study Protocol – A randomized controlled trial to evaluate a proactive approach to health care in Parkinson’s disease
Objective: To implement and evaluate a novel care model for people with Parkinson’s Disease (PD), based on the following principles: proactive, person-centered, and digital (cf.…Non-invasive Vagus Nerve Stimulation Alters Molecular Markers in Parkinson’s Disease Patients with Freezing of Gait
Objective: To investigate molecular mechanisms underlying non-invasive vagus nerve stimulation (nVNS) in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: FOG remains one…Subjective cognitive complaints in participants of the Healthy Brain Ageing (HeBA) study
Objective: To investigate the prevalence of subjective cognitive complaints (SCC) from Healthy Brain Ageing Study (HeBA) participants in Luxembourg, and explore risk factors prevalence which…Unusual Neuronal Intranuclear Inclusion Disease (NIID) with initial presentation mimicking recurrent Transient Global Amnesia (TGA)
Objective: Our aim is to report an unusual Neuronal intranuclear inclusion disease (NIID) case of a woman who initially presented recurrent Transient Global Amnesia (TGA)…
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