Using mediation analysis to account for the effect of Parkinson’s Disease medications on disease progression
Objective: To explore the use of mediation analysis to incorporate L-dopa equivalent daily dose (LEDD) for disease progression of Parkinson’s Disease (PD) in a simulation…MRgFUS thalamotomy in dystonic and essential tremor: a prospective study with one year follow up
Objective: The primary objective of this study was to evaluate the effectiveness of MRgFUS thalamotomy in patients with Dystonic Tremor (DT) compared with patients with…Directional deep brain stimulation therapy in the long term
Objective: To describe our long-term clinical experience with directional deep brain stimulation (d-DBS) in patients with advanced Parkinson’s disease (PD) who have been implanted with…10 year longitudinal change in clinical and biological characteristics of sporadic Parkinson Disease PPMI cohort
Objective: To present data on 10 year longitudinal clinical and biological characteristics of sporadic Parkinson Disease (sPD) participants in the Parkinson’s Progression Markers Initiative (PPMI)…Parkinson’s Disease and Chronic Inflammatory Demyelinating Polyneuropathy: Broadening the Clinical Spectrum of VCP Mutations?
Objective: Valosin-containing protein (VCP) mutation causes a multiorgan disease characterized by inclusion body myopathy, Paget disease and frontotemporal dementia, more rarely by Charcot-Marie-Tooth disease type…An acoustic-perceptual analysis of speech in clinical PSP phenotypes.
Objective: To examine the speech profile in a cohort of patients with Progressive Supranuclear Palsy with Richardson’s syndrome (PSP-RS) and PSP with predominant parkinsonism (PSP-P)…The investigation of a novel video game for identifying mild cognitive impairment in individuals with Parkinson’s disease
Objective: To develop a novel video game (VG) prototype that can effectively detect mild cognitive impairment (MCI) in Parkinson’s disease (PD) patients. Background: MCI is…Chinese proprietary medicine as adjunct treatment for Parkinson’s disease: a systematic review and meta-analysis
Objective: To evaluate the effectiveness of Chinese proprietary medicine (CPM) in improving outcomes of Parkinson’s disease (PD). Background: CPM is a finished Chinese herbal medicine…Comparison of original and revised versions of the University of Pennsylvania Smell Identification Test
Objective: To assess agreement between the original and revised versions of the University of Pennsylvania Smell Identification Test (UPSIT). Background: Recently published age/sex-specific UPSIT percentiles,…Effect of multi-strain probiotics on gut microbiome and metabolites in Parkinson’s Disease
Objective: We investigated the effects of multi-strain probiotics administration on gut microbiome and metabolites, and markers of intestinal permeability and inflammation. Background: Probiotics have been…
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