Development of therapeutic substances for the disassembly of α-synuclein aggregates as disease-modifying treatment of synucleinopathies
Objective: Development of high-affinity ligands to α-synuclein (α-syn) for a therapeutic approach aiming for the disassembly of α-syn aggregates as a disease-modifying treatment of synucleinopathies.…Diagnostic and treatment burden of dystonia in Turkey: a patient journey map
Objective: To assess the burden of access to diagnosis and botulinum neurotoxin (BoNT) treatment in Turkish patients with dystonia and hemifacial spasm (PwD/HFS). Background: Diagnostic…REM sleep behaviour disorder in Parkinson’s disease: prevalence and correlation with other sleep parameters
Objective: to assess the prevalence of probable rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD) patients and its correlation with other…Weighing tremor reduction and side effects: Impact of efficacy and safety outcomes on patient satisfaction at 6 months in MR-guided focused ultrasound thalamotomy for tremor treatment
Objective: To relate efficacy and safety outcomes to patient satisfaction at 6 months after MR-guided focused ultrasound (MRgFUS) thalamotomy in the ventral intermediate nucleus (VIM)…Parkinson’s Progression Markers Initiative (PPMI): Defining PD biology to accelerate PD therapeutics
Objective: The overall goal of PPMI is to identify, test and validate biomarkers of PD to accelerate therapeutic development throughout the PD continuum. Background: PPMI…National Luxembourg Sleep Study: An enriched, at risk, prodromal Parkinson’s Disease cohort
Objective: To identify a cognitively intact enriched cohort of people with isolated rapid eye movement (iREM) sleep behaviour disorder (iRBD) and hyposmia, at risk of…Filipino’s and Parkinson’s Disease: A Scoping Review of the Literature
Objective: To review the literature on Parkinson’s disease (PD) in Filipino’s and identify specific studies focusing on Filipino-Americans and Parkinson’s disease. Background: Filipino’s are the…REM sleep behavior disorder in Parkinson´s Disease: a risk factor for Impulse Control Disorders.
Objective: We aimed to analyze de association between REM sleep behavior disorder (RBD) and impulse control disorders (ICD) in Parkinson´s disease (PD) patients and in…Neurologic music therapy for fine motor rehabilitation in Huntington’s disease: a pilot study
Objective: To present preliminary evidence of fine motor rehabilitation in patients with Huntington’s disease using neurologic music therapy. Background: Huntington’s disease (HD) is an autosomal…Increased incidence of Functional movement disorders during COVID-19 pandemic
Objective: To assess the frequency of functional movement disorders (FMD) during the COVID-19 pandemic in comparison to the pre-pandemic period and to identify factors causing…
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